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Meaning-Centered Psychotherapy in Advanced Cancer

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00067288
Recruitment Status : Completed
First Posted : August 15, 2003
Last Update Posted : August 18, 2006
Information provided by:
National Center for Complementary and Integrative Health (NCCIH)

August 14, 2003
August 15, 2003
August 18, 2006
May 2002
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Complete list of historical versions of study NCT00067288 on Archive Site
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Meaning-Centered Psychotherapy in Advanced Cancer
Meaning-Centered Psychotherapy in Advanced Cancer
We have developed an 8-week Meaning-Centered Group Psychotherapy designed to help patients with advanced cancer sustain or enhance a sense of meaning, peace and purpose despite the limitations of their cancer illness. This project's overall aim is to explore the feasibility and efficacy of this new and unique psychotherapy intervention for advanced cancer patients in enhancing psychological and spiritual well-being and quality of life by comparing it with a standard supportive group psychotherapy.
As per Brief Summary
Phase 2
Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Educational/Counseling/Training
  • Lymphoma, Non-Hodgkin
  • Neoplasms
  • Behavioral: Meaning-Centered Group Psychotherapy
  • Behavioral: Standard Supportive Group Psychotherapy
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*   Includes publications given by the data provider as well as publications identified by Identifier (NCT Number) in Medline.
March 2006
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Inclusion Criteria:

  • 21 years of age or older;
  • English speaking;
  • Stage III or IV solid-tumor or Non-Hodgkin's Lymphoma;
  • Receiving ambulatory care at Memorial Sloan-Kettering Cancer Center in New York City;

Exclusion Criteria:

  • Significant psychiatric disturbance sufficient, in the investigator's judgment, to preclude participation in a group-format intervention;
  • Presence of cognitive impairment disorder, such as delirium or dementia that is sufficient, in the investigator's opinion, to preclude meaningful participation and/or informed consent;
  • Karnofsky Performance Rating Scale below 50 or physical limitations or illness severity sufficient to preclude participation in outpatient group psychotherapy.
Sexes Eligible for Study: All
21 Years and older   (Adult, Senior)
Contact information is only displayed when the study is recruiting subjects
United States
R21AT001031-01( U.S. NIH Grant/Contract )
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National Center for Complementary and Integrative Health (NCCIH)
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Principal Investigator: William Breitbart, MD Memorial Sloan Kettering Cancer Center
Investigator: Christopher Gibson, PhD Project Coordinator Memorial Sloan-Kettering Cancer Center
National Center for Complementary and Integrative Health (NCCIH)
August 2006

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP