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Protection Against Benzene Toxicity

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00011453
First Posted: February 23, 2001
Last Update Posted: December 9, 2005
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
National Institute of Environmental Health Sciences (NIEHS)
February 21, 2001
February 23, 2001
December 9, 2005
July 1998
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No Changes Posted
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Protection Against Benzene Toxicity
NQO1 in Protection Against Benzene Toxicity
We are investigating the role of an enzyme (NQO1) in protection against the bone marrow toxicity of the occupational and environmental toxicant benzene. All of the proposed studies involve use of human bone marrow cells in-vitro to define mechanisms of NQO1-mediated protection. Cells are obtained from healthy volunteers and protocols have undergone IRB review and approval.
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Observational
Primary Purpose: Screening
Time Perspective: Prospective
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  • Leukemia
  • Aplastic Anemia
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
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June 2001
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Healthy adult volunteers with blood counts in normal ranges and without evidence of hepatitis or HIV infection.
Sexes Eligible for Study: All
21 Years to 65 Years   (Adult)
Yes
Contact information is only displayed when the study is recruiting subjects
United States
 
 
NCT00011453
9554-CP-001
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National Institute of Environmental Health Sciences (NIEHS)
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National Institute of Environmental Health Sciences (NIEHS)
July 2002