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Suppressed Anger, Blood Pressure and Mortality Follow-up

This study has been completed.
Sponsor:
Information provided by:
National Heart, Lung, and Blood Institute (NHLBI)
ClinicalTrials.gov Identifier:
NCT00005458
First received: May 25, 2000
Last updated: May 12, 2016
Last verified: May 2000

May 25, 2000
May 12, 2016
January 1991
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Complete list of historical versions of study NCT00005458 on ClinicalTrials.gov Archive Site
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Suppressed Anger, Blood Pressure and Mortality Follow-up
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To re-examine the relationship between suppressed anger, elevated blood pressure and all-cause as well as coronary heart disease (CHD) mortality using data from the Life Change Event Study (LCES) conducted on a representative sample of the Tecumseh Community Health Study (TCHS), n=696, men and women, aged 30-69 in 1971-1972.

DESIGN NARRATIVE:

The psychosocial data (e.g. anger-expression, stressful life events) and some medical data (e.g. blood pressure, smoking) were collected in 1971/72, while additional information about other medical risk factors was collected in 1968/69. Mortality ascertainment and cause of death was completed by the end of 1989, through TCHS staff, using the National Death Index (NDI). The estimated cumulative 18-year mortality rate as of 1989 for the Tecumseh cohort of the same age as the LCES sample was 26 percent for males and 16 percent for females. Approximately 144 deaths were expected. Out of the total TCHS cohort deaths, 35 percent were estimated to be due to CHD. Research questions tested included: (1) did suppressed anger predict coronary heart disease mortality as well as all-cause mortality; (2) was the relationship between suppressed anger and mortality modified by other risk factors (e.g. blood pressure, marital stress, gender); (3) were there certain anger-coping strategies among married couples which increased mortality risk for one or both members of the marital pair.

Analyses were done at three levels: for the whole sample, separately for males and females, and for a subgroup of 192 married couples it was done by 'pairs'. To determine univariate association between anger-coping types and all-cause mortality, the percent deceased was compared among persons grouped according to their anger responses. For the situation-specific and total suppressed anger indices, the distribution of scores was divided into thirds. The significance of each association was tested using chi-square statistics. Logistic regression was employed to test for the significance of the association between anger-coping measures and mortality controlling for sex, age, education, marital stress, relative weight, smoking, systolic blood pressure, CHD status, bronchitis, and FEV1 scores. Logistic regression was also used to determine whether any of the risk factors, particularly blood pressure, gender and marital stress, significantly modified the relationship between suppressed anger and mortality. The design and measures of this study had the potential to further identify specific person-situation characteristics associated with higher risks of total as well as cause specific mortality which then could be used to make more knowledgeable recommendations for health behavior interventions.

The study completion date listed in this record was obtained from the "End Date" entered in the Protocol Registration and Results System (PRS) record.

Observational
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  • Cardiovascular Diseases
  • Heart Diseases
  • Coronary Disease
  • Hypertension
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
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December 1991
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No eligibility criteria
Male
up to 100 Years   (Child, Adult, Senior)
No
Contact information is only displayed when the study is recruiting subjects
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NCT00005458
4902, R01HL041796
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National Heart, Lung, and Blood Institute (NHLBI)
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National Heart, Lung, and Blood Institute (NHLBI)
May 2000

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP