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Idiopathic Pulmonary Fibrosis: a Case-control Study

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00005295
First Posted: May 26, 2000
Last Update Posted: January 15, 2016
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Collaborator:
National Heart, Lung, and Blood Institute (NHLBI)
Information provided by:
University of New Mexico
May 25, 2000
May 26, 2000
January 15, 2016
July 1989
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Complete list of historical versions of study NCT00005295 on ClinicalTrials.gov Archive Site
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Idiopathic Pulmonary Fibrosis: a Case-control Study
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To determine risk factors for idiopathic pulmonary fibrosis.

BACKGROUND:

Idiopathic pulmonary fibrosis is a progressive and generally fatal disease that causes fibrosis of the pulmonary interstitium. While many environmental agents cause diseases clinically similar, the etiology of idiopathic pulmonary fibrosis suggests that environmental agents could incite the tissue injury that results in the disease; furthermore, host characteristics could have an important role in determining the magnitude of the host response to the agent initiating injury.

DESIGN NARRATIVE:

In this case control study, cases were ascertained at the multiple collaborating centers and controls were identified by telephone screening. A telephone interview was conducted to collect information needed to test hypotheses concerning cigarette smoking, occupational exposure, indoor exposures, other environmental factors, and host factors. To limit disease misclassification, two pathologists experienced with interstitial diseases of the lung reviewed histopathological material from all cases to exclude entities other than interstitial lung fibrosis and to fully characterize the cases clinically. The mortality of this large series of cases was also described.

Observational
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  • Lung Diseases
  • Pulmonary Fibrosis
  • Lung Diseases, Interstitial
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
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June 1995
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No eligibility criteria
Sexes Eligible for Study: Male
up to 100 Years   (Child, Adult, Senior)
No
Contact information is only displayed when the study is recruiting subjects
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NCT00005295
2018
R01HL043153 ( U.S. NIH Grant/Contract )
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University of New Mexico
National Heart, Lung, and Blood Institute (NHLBI)
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University of New Mexico
January 2016