We updated the design of this site on September 25th. Learn more.
Show more
ClinicalTrials.gov
ClinicalTrials.gov Menu

Evaluation of the Genetics of Bipolar Disorder

This study is currently recruiting participants.
Verified August 1, 2017 by National Institutes of Health Clinical Center (CC) ( National Institute of Mental Health (NIMH) )
Sponsor:
ClinicalTrials.gov Identifier:
NCT00001174
First Posted: November 4, 1999
Last Update Posted: August 7, 2017
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.
Information provided by (Responsible Party):
National Institutes of Health Clinical Center (CC) ( National Institute of Mental Health (NIMH) )
November 3, 1999
November 4, 1999
August 7, 2017
August 4, 1980
Not Provided
Not Provided
Not Provided
Complete list of historical versions of study NCT00001174 on ClinicalTrials.gov Archive Site
Not Provided
Not Provided
Not Provided
Not Provided
 
Evaluation of the Genetics of Bipolar Disorder
Bipolar Genetics: A Collaborative Study
This study looks to identify genes that may affect a person's chances of developing bipolar disorder (BP) and related conditions.

Bipolar affective disorder is a severe, heritable condition affecting about one percent of

the population. The mode of inheritance is poorly understood and probably involves multiple loci of small to moderate effect. In this project, we use genetic mapping and sequencing methods to identify genetic markers and variations that contribute to the risk of bipolar disorder. Individuals diagnosed with bipolar disorder are studied, along with their relatives. Phenotypic information obtained from clinical interviews and family history is correlated with genotypic information obtained from genetic marker and sequencing methods. The goal is to identify genes involved in bipolar disorder and related conditions so that better methods of diagnosis, treatment, and prevention can be developed.

Observational
Observational Model: Family-Based
Time Perspective: Retrospective
Not Provided
Not Provided
Not Provided
Not Provided
  • Mania
  • Bipolar, Disorder
  • Depression
  • Mood Disorder
  • Schizoaffective
  • Manic Depression
Not Provided
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruiting
4000
Not Provided
Not Provided
  • INCLUSION CRITERIA:

Age > 18 yr

Able to provide informed consent

Diagnosed with bipolar disorder not attributable to substance abuse, neurological disease; or a 1st or 2nd degree relative of an enrolled participant

Able to safely provide a blood or saliva sample

EXCLUSION CRITERIA:

Active alcohol or substance abuse.

NIMH employees/staff and their immediate family members will be excluded from the study per NIMH policy.

Sexes Eligible for Study: All
18 Years to 85 Years   (Adult, Senior)
No
Contact: Emily Besancon (301) 594-0576 emily.besancon@nih.gov
Contact: Francis J McMahon, M.D. (301) 451-4453 mcmahonf@mail.nih.gov
United States
 
 
NCT00001174
800083
80-M-0083
Not Provided
Not Provided
Not Provided
National Institutes of Health Clinical Center (CC) ( National Institute of Mental Health (NIMH) )
National Institute of Mental Health (NIMH)
Not Provided
Principal Investigator: Francis J McMahon, M.D. National Institute of Mental Health (NIMH)
National Institutes of Health Clinical Center (CC)
August 1, 2017