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Study of the Psychological Development of Children of Parents With and Without Affective Disorders

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT00001170
Recruitment Status : Completed
First Posted : November 4, 1999
Last Update Posted : March 4, 2008
Sponsor:
Information provided by:

November 3, 1999
November 4, 1999
March 4, 2008
October 1979
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Complete list of historical versions of study NCT00001170 on ClinicalTrials.gov Archive Site
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Study of the Psychological Development of Children of Parents With and Without Affective Disorders
Affective Disorders and Affective Development: A Study of Child Rearing and Child Development in Normal Families and Families With Affective Disorders

This research study is the continuation of a study started more than 20 years ago. The study was designed to explore the effect that depressed parents have on their children and to better understand the factors that contribute to depression development and maintenance.

The study will continue to investigate if children have certain characteristics in early and middle childhood that predict the later development of psychological disorders.

In addition, the study will continue looking at the processes responsible for the development of children of parents with and without affective (mood) disorders.

The psychological development of offspring of parents with and without affective disorder is assessed from early childhood to young adulthood. Parents with a diagnosis of major depression or bipolar illness and well parents and their children are studied (SADS-L, RDC, and SCID, DSM-III). A sibling pair is studied in each family. Parent-child interaction is investigated through direct observation of behavior in naturalistic and controlled settings. Family history information is obtained through parent interviews. Behavioral observations, standard tests, physical examinations, and psychiatric interviews, and MRI procedures provide multiple assessments of the offspring. The study has been completed through preadolescence, adolescence, and late adolescence. Follow-up in young adulthood continues.
Observational
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  • Bipolar Disorder
  • Involutional Depression
  • Mood Disorder
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
1045
February 2005
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Patients will be drawn from an ongoing longitudinal study begun in 1979 of offspring of parents with affective illness (unipolar and bipolar) and children of normal control parents.
Sexes Eligible for Study: All
Child, Adult, Senior
Yes
Contact information is only displayed when the study is recruiting subjects
United States
 
 
NCT00001170
790123
79-M-0123
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National Institute of Mental Health (NIMH)
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National Institutes of Health Clinical Center (CC)
February 2005