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Comparison of Perioperative Analgesic Efficacy of Femoral Nerve Block, Adductor Canal Block and 4in1 Block

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ClinicalTrials.gov Identifier: NCT05643040
Recruitment Status : Recruiting
First Posted : December 8, 2022
Last Update Posted : December 8, 2022
Sponsor:
Information provided by (Responsible Party):
Funda Atar, Diskapi Yildirim Beyazit Education and Research Hospital

Study Description
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Brief Summary:
Central neuraxial and regional anesthesia and analgesia techniques significantly reduce perioperative morbidity and mortality in the knee and below-knee surgeries.Nerve blocks appear to have better analgesic efficacy compared to placebo or patient-controlled analgesia (PCA). In addition, opioid-related side effects such as postoperative nausea, vomiting, pruritus, sedation, and respiratory depression are less. Therefore, interest in regional blocks such as femoral, sciatic, adductor, combined femoral, and sciatic is increasing. The knee joint is innervated by various nerves (genicular nerves) from the femoral, obturator, and sciatic nerves, and a comprehensive but simple technique is needed for postoperative analgesia. Complete and comprehensive postoperative analgesia was possible with this block, a simple single injection technique. The aim of our study is to evaluate the intraoperative analgesia efficacy of femoral, adductor canal block, and 4in1 block in patients who will undergo knee surgery.

Condition or disease Intervention/treatment Phase
Block Analgesia Other: femoral nerve block Other: adductor canal block Other: 4in1 block Not Applicable

Study Design
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Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 60 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Intervention Model Description: Group I: Femoral nerve block Group II: Adductor canal block Group III: 4in1 block
Masking: Single (Participant)
Primary Purpose: Other
Official Title: Comparison of Perioperative Analgesic Efficacy in Patients Who Had Femoral Nerve Block, Adductor Canal Block and 4in1 Block Applied in Knee Surgery
Actual Study Start Date : September 1, 2022
Estimated Primary Completion Date : February 1, 2023
Estimated Study Completion Date : May 1, 2023

Resource links provided by the National Library of Medicine


Arms and Interventions
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Arm Intervention/treatment
Experimental: femoral nerve block
To evaluate the intraoperative analgesia effectiveness of femoral nerve block in patients who will have knee surgery.
 Other: femoral nerve block
To evaluate the intraoperative analgesia effectiveness of femoral block in patients who will have knee surgery.
Experimental: adductor canal block
To evaluate the intraoperative analgesia effectiveness of adductor canal block in patients who will have knee surgery.
 Other: adductor canal block
To evaluate the intraoperative analgesia effectiveness of adductor canal block in patients who will have knee surgery.
Experimental: 4in1 block
To evaluate the intraoperative analgesia effectiveness of 4in1 block in patients who will have knee surgery.
 Other: 4in1 block
To evaluate the intraoperative analgesia effectiveness of 4in1 block in patients who will have knee surgery.


Outcome Measures
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Primary Outcome Measures :
  1. intraoperative analgesia efficacy [ Time Frame: perioperative period ]
    The aim of our study is to evaluate the intraoperative analgesia efficacy of femoral, adductor canal block and 4in1 block in patients who will undergo knee surgery.


Secondary Outcome Measures :
  1. postoperative analgesia efficacy [ Time Frame: perioperative period ]
    The aim of our study is to evaluate the postoperative analgesia efficacy of femoral, adductor canal block and 4in1 block in patients who will undergo knee surgery.


Eligibility Criteria
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Ages Eligible for Study:   18 Years to 99 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Patients between the ages of >18
  • undergone knee surgery
  • American Society of Anesthesiologists (ASA) classification I-III group.

Exclusion Criteria:

  • Patients who do not want to participate in the study coagulopathy peripheral neuropathy local anesthetic drug allergy chronic opioid users anticoagulant users pregnant patients
Contacts and Locations
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Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT05643040


Contacts
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Contact: Funda Atar, MD 5064927432 fundaatar81@gmail.com

Locations
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Turkey
University of Medical Science, Yıldırım Beyazıt Training and Research Hospital Recruiting
Ankara, Turkey, 06000
Contact: Funda Atar, MD         
Sponsors and Collaborators
Diskapi Yildirim Beyazit Education and Research Hospital
More Information
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Publications:

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Responsible Party: Funda Atar, Diskapi Yildirim Beyazit Education and Research Hospital
ClinicalTrials.gov Identifier: NCT05643040    
Other Study ID Numbers: 06/06/2022 139/13
First Posted: December 8, 2022    Key Record Dates
Last Update Posted: December 8, 2022
Last Verified: December 2022
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Keywords provided by Funda Atar, Diskapi Yildirim Beyazit Education and Research Hospital:
4 in 1 block
femoral block
adductor canal block