Surgical Management and Outcome of Tethered Cord Syndrome
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government.
Know the risks and potential benefits of clinical studies and talk to your health care provider before participating.
Read our disclaimer for details.
The aim of this study is to assess surgical management and outcome of Tethered cord syndrome
Condition or disease
Tethered Cord Syndrome
Procedure: Detethering of the spinal cord
Tethered cord syndrome (TCS) is a developmental abnormality of the neuroaxis which is usually diagnosed in childhood. The actual tethering has been attributed to a variety of pathologic entities, including a thickened tight filum terminale , intradural lipomas with or without a connecting extradural component, intradural fibrous adhesions, diastematomyelia, and adherence of the neural placode following previous closure of a myelomeningocele. However, sufficient differences in the mode of onset, clinical manifestations, and outcome exist between pediatric and adolescent patients with tethered cord to warrant a more detailed analysis of the adult syndrome. The most problematic technical consideration in surgery for the release of the tethered cord is how to preserve functioning neural elements and rebuild the dural sac to avoid CSF leak. The purpose of this study is to review causes of Tethered cord, clinical presentation, diagnostic tools, treatment options and outcome in school-aged children, adolescents, and young adults with Tethered cord.
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
Layout table for eligibility information
Ages Eligible for Study:
1 Year to 16 Years (Child)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Males and Females below 16 years old with Tethered cord syndome
Patients with Tethered cord syndrome presenting at our institute
Patients with spinal dysraphism
Lipomyelomeningocele with Tethered cord
patients presented with neurological deficit after lipomyelomeningocele repair due to Tethered cord
patients presented with neurological deficit after myelomeningocele repair due to Tethered cord
Diastematomyelia with Tethered cord - Tethered cord due to filum terminale.
Tethered cord due to fibrous adhesions
Asymptomatic Patients with Tethered cord discovered accidentally