Melatonin Levels on COVID-19 Positive Pregnant Women
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|ClinicalTrials.gov Identifier: NCT05318144|
Recruitment Status : Completed
First Posted : April 8, 2022
Last Update Posted : April 8, 2022
This study aimed to investigate the prognostic value of serum melatonin as a biomarker for the determination of severe COVID-19 infection in pregnant women.
Four study groups were formed, including pregnant women with a positive COVID-19 PCR test, severe symptoms, and inpatient treatment. Pregnant women who had complaints similar to COVID-19 infection or had no complaints, but had a PCR test due to the surveillance program and negative test results were included in the control group.
Methods and Main Outcome measure: Laboratory values of the cases at the time of diagnosis parameters were collected.
Melatonin levels decrease in pregnant women with COVID-19 symptoms, the severity of symptoms increases. In addition, patients with low melatonin levels have an increase in infection parameters and an increase in the hospital stay.
|Condition or disease|
|COVID-19 Acute Respiratory Distress Syndrome Pregnancy Related Pregnancy Complications|
|Study Type :||Observational [Patient Registry]|
|Actual Enrollment :||228 participants|
|Target Follow-Up Duration:||6 Months|
|Official Title:||Prognostic Value of Serum Melatonin as a Biomarker for the Determination of Severe COVID-19 Infection in Pregnant Women|
|Actual Study Start Date :||June 1, 2021|
|Actual Primary Completion Date :||December 1, 2021|
|Actual Study Completion Date :||February 1, 2022|
PCR (-) symptomatic
control group, pregnant women with negative COVID-19 Polymerase Chain Reaction (PCR) test
PCR (+) asymptomatic
Pregnant women who have a positive COVID-19 PCR test and have had the infection without symptoms
PCR (+) mild-moderate
Pregnant women with positive COVID-19 PCR test and mild to moderate symptoms and inpatient treatment
PCR (+) severe COVID-19
Pregnant women with positive COVID-19 PCR test and severe symptoms
- Melatonin level [ Time Frame: 6 year ]Melatonin level of pregnant women with COVID-19
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT05318144
|Samsun Training and Research Hospital|
|Samsun, Turkey, 58153|
|Study Chair:||Serkan Oral||Halic University Faculty of Medicine, Department of Obstetrics and Gynecology|