Venous thromboEmbolism Risk Profiles in Chinese hoSpitalized patiEnts (VERSE Study)
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|ClinicalTrials.gov Identifier: NCT05058521|
Recruitment Status : Completed
First Posted : September 27, 2021
Last Update Posted : September 27, 2021
|Condition or disease|
In this study, the investigators recruited adult inpatients attending Tsinghua Chang Gung Hospital in Beijing from June 2018 to April 2020, screened for patients with a hospital stay over 3 days and new-onset of VTE during hospital stay, and identified the in-hospital VTE patients after excluding patients who presented for DVT and/or PE. Similarly, negative patients were selected by not having a VTE during hospital stay. The diagnosis of VTE was confirmed as the occurrence of a critical value alert during hospitalization, which was predefined as ultrasound/radiology report of DVT or/and PE. Data was collected from the TEACH database of Beijing Tsinghua Chang Gung Hospital affiliated with Tsinghua University.
Patients baseline characteristics were extracted from database. VTE risk assessment was conducted with either Caprini risk assessment model (surgical patients) or Padua prediction score (medical patients). The evaluation was started upon admission and regularly repeated depending on the patient's condition. The last evaluation was conducted before discharge. The D-dimer values during hospitalization were also collected.
The rate of in-hospital VTE, distributions of in-hospital VTE patients and the receiver operating characteristic curves were analyzed.
|Study Type :||Observational [Patient Registry]|
|Actual Enrollment :||27490 participants|
|Target Follow-Up Duration:||23 Months|
|Official Title:||Venous Thromboembolism Risk Profiles Among Hospitalized Patients in Chinese General Hospital- a Cross-sectional Single-institution Based Study|
|Actual Study Start Date :||June 1, 2018|
|Actual Primary Completion Date :||April 30, 2020|
|Actual Study Completion Date :||April 30, 2020|
In-hospital VTE group
In-hospital VTE group includes patients who were with a hospital stay over 3 days and new-onset of VTE during their stay. Patients who presented for VTE were excluded.
Negative group includes patients who were with a hospital stay over 3 days and did not have a VTE during their hospital stay.
- The rate of in-hospital VTE [ Time Frame: From June 2018 to April 2020 ]The diagnosis of VTE was confirmed as the occurrence of a critical value alert during hospitalization, which was predefined as ultrasound/radiology report of DVT or/and PE.
- Caprini risk assessment model scores [ Time Frame: Through discharge, an average of 20 days ]Patients were stratified of VTE risk as very low risk (0), low risk (1-2), medium risk (3-4), high risk (5 and over).
- Padua prediction score scores [ Time Frame: Through discharge, an average of 20 days ]Patients were stratified of VTE risk as low risk (0-3) and high risk (4 and over).
- D-dimer values [ Time Frame: Through discharge, an average of 20 days ]The upper normal value 0.55mg/L FEU was used.
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Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT05058521
|Beijing Tsinghua Chang Gung Hosipital|
|Beijing, China, 102218|
|Principal Investigator:||Weiwei Wu, MD||Beijing Tsinghua Chang Gung Hospital|