LOng COvid Multidisciplinary Consortium: Optimising Treatments and servIces Across the NHS (LOCOMOTION) (LOCOMOTION)
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|ClinicalTrials.gov Identifier: NCT05057260|
Recruitment Status : Recruiting
First Posted : September 27, 2021
Last Update Posted : November 3, 2022
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Background: Long Covid (LC) affects over one million people in the UK, it has various symptoms and impacts daily life. Although there are 83 LC clinics in England, most people have not had access to them, and waiting times to be seen are long. We realise the urgency for LC patients to access prompt and appropriate care in clinics and doctors' surgeries, as well as manage their symptoms effectively at home.
Aim:Our research aims to produce a 'gold standard' for care by analysing what is happening to patients now, creating new systems of care and evaluating them to establish best practice.
Outline Of Research: This research has been developed with LC patients and will continue to include patients working as equal partners. Key priorities of LC patients are: correct clinical assessment; advice and treatment; and help with returning to work and other roles. This research is also based on the experience of a wide range of NHS professionals already treating people in ten LC clinics across the UK, and led by academics (universities) with links to other LC funded studies.
The research will take place in three settings: LC clinics; at home (including self-monitoring on a mobile device using a set of questions on symptoms built into an app); and in doctors' surgeries. We will track where patients are being referred or not referred, and learn from the experience of clinics by interviewing patients and recording outcomes. Throughout, specialists in 'Healthcare Inequality' will reach people who are not accessing clinics. We will put in place new processes in clinics and doctors' surgeries, monitored throughout to make sure they are the correct standard, accessible for patients and staff, and cost-effective.
Outcomes: Comparing findings across our partnership of ten LC Clinics we will learn more about treatment, providing real-time education to other healthcare staff and patients, and establishing a 'gold standard' that can be shared within England and the rest of the UK.
|Condition or disease||Intervention/treatment|
|COVID-19||Other: No drug invervention|
|Study Type :||Observational|
|Estimated Enrollment :||7000 participants|
|Official Title:||LOng COvid Multidisciplinary Consortium: Optimising Treatments and servIces Across the NHS (LOCOMOTION)|
|Actual Study Start Date :||January 18, 2022|
|Estimated Primary Completion Date :||December 31, 2023|
|Estimated Study Completion Date :||December 31, 2024|
Long Covid cohort
Long Covid patients managed in the 10 participating sites
Other: No drug invervention
No clinical trial
- European Quality of Life Five Dimensions [ Time Frame: 2 years ]Quality of Life VAS score min 0 max 100
- COVID-19 Yorkshire Rehabilitation Scale [ Time Frame: 2 years ]Symptom severity (min 0 max 100) and functional disability (min 0 max 50) and health state (min 0 max 10)
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|Ages Eligible for Study:||18 Years and older (Adult, Older Adult)|
|Sexes Eligible for Study:||All|
|Accepts Healthy Volunteers:||No|
|Sampling Method:||Non-Probability Sample|
- Age 18 and over, receiving care for Long Covid symptoms at one of the participating LC sites.
- Willing and able to consent for their data to be used for research and/or service evaluation purposes. Consent will be gathered via patient information sheet and formal recording of consent (on the phone application).
- Inability to independently complete electronic or paper-based outcome measures, questionnaires or other research-based paperwork.
- Unable to give Informed Consent.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT05057260
|Contact: Manoj Sivan, MDemail@example.com|
|University of Leeds||Recruiting|
|Leeds, Yorkshire, United Kingdom, LS1 3EX|
|Contact: Manoj Sivan, MD firstname.lastname@example.org|
|Principal Investigator:||Manoj Sivan, MD||University of Leeds|
|Responsible Party:||Dr Manoj Sivan, Associate Professor and Consultant in Rehabilitation Medicine, University of Leeds|
|Other Study ID Numbers:||
|First Posted:||September 27, 2021 Key Record Dates|
|Last Update Posted:||November 3, 2022|
|Last Verified:||October 2022|
|Individual Participant Data (IPD) Sharing Statement:|
|Plan to Share IPD:||Undecided|
|Studies a U.S. FDA-regulated Drug Product:||No|
|Studies a U.S. FDA-regulated Device Product:||No|
Post-Acute COVID-19 Syndrome
Respiratory Tract Infections
RNA Virus Infections
Respiratory Tract Diseases