Prediction of Chronic Kidney Disease Following Pre-eclampsia: Diagnosis and Early Care (PRECEDE)
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|ClinicalTrials.gov Identifier: NCT05056701|
Recruitment Status : Recruiting
First Posted : September 24, 2021
Last Update Posted : October 5, 2021
Pre-eclampsia (PE) is a pregnancy-associated syndrome of variable severity, classically defined by the combination of hypertension and proteinuria in a previously non-hypertensive or proteinuric patient. These symptoms normally resolve within 2-3 months after delivery regardless of the severity of the pre-eclampsia.
Regardless of its definition, preeclampsia is associated with an increased risk of obstetric events and, for the mother, an increased risk of developing chronic kidney disease (CKD), hypertension, diabetes and cardiovascular disease in the broad sense.
The relationship between preeclampsia and Chronic Kidney Disease is, however, complex and not fully understood.
Investigator proposes an interventional study to identify the diagnosis of Chronic Kidney Disease in patients who have developed an episode of Preeclampsia.
|Condition or disease||Intervention/treatment||Phase|
|Preeclampsia||Other: annual follow-up during 10 years||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||400 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Official Title:||Prediction of Chronic Kidney Disease Following Pre-eclampsia: Diagnosis and Early Care|
|Actual Study Start Date :||August 5, 2021|
|Estimated Primary Completion Date :||August 5, 2036|
|Estimated Study Completion Date :||August 5, 2036|
Experimental: patient with preeclampsia
Patient meeting preeclampsia criteria according to International Society for the Study of Hypertension in Pregnancy (ISSHP) 2018 definitions
Other: annual follow-up during 10 years
an annual follow-up is carried out systematically for a total of 10 years in order to detect the subsequent occurrence of CKD
- prevalence of the Chronic Kidney Disease (CKD) [ Time Frame: until 10 years ]prevalence of the CKD is measured by the the rate of new CKD Diagnoses (according to the standard definitions)
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT05056701
|Contact: Christelle JADEAU||02 44 71 07 email@example.com|