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Clinical Isolation Syndrome of Spinal Cord and Multiple Sclerosis

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT04952246
Recruitment Status : Recruiting
First Posted : July 7, 2021
Last Update Posted : July 7, 2021
Sponsor:
Information provided by (Responsible Party):
Peking University Third Hospital

Study Description
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Brief Summary:
The purpose of this study was to investigate the factors that influence the progression of patients with clinically isolated spinal cord syndrome to multiple sclerosis.

Condition or disease
Clinical Isolation Syndrome of Spinal Cord Multiple Sclerosis

Detailed Description:
This study included patients who were first diagnosed with clinically isolated spinal cord syndrome admitted to the Department of Neurology, Peking University Third Hospital between January 2010 and November 2020. According to the result of the outcome is divided into multiple sclerosis and outcome group, analyzing the characteristics of the age, sex, clinical manifestations, imaging features, evoked potential, blood immune antibody results, rate of cerebrospinal fluid routine biochemical synthesis oligoclonal band IgG, extension, nerve dysfunction score spinal cord clinically isolated syndrome and the influence factors, such as the relationship between the outcome of multiple sclerosis.
Study Design
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Study Type : Observational
Estimated Enrollment : 150 participants
Observational Model: Case-Control
Time Perspective: Retrospective
Official Title: Clinical Isolated Spinal Cord Syndrome Was Identified as Multiple Sclerosis Associated Risk Factor Analysis
Actual Study Start Date : January 1, 2010
Actual Primary Completion Date : November 30, 2020
Estimated Study Completion Date : November 30, 2023

Resource links provided by the National Library of Medicine


Groups and Cohorts
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Group/Cohort
multiple sclerosis group
non-prognosis group


Outcome Measures
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Primary Outcome Measures :
  1. Progressed to multiple sclerosis [ Time Frame: 3 years ]
    Progressed to multiple sclerosis


Eligibility Criteria
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Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
clinically isolated spinal cord syndrome
Criteria

Inclusion Criteria:

Diagnosis time and place: Department of Neurology, Peking University Third Hospital from January 2010 to November 2020 Diagnosed as a patient with clinically isolated spinal cord syndrome for the first time

Exclusion Criteria:

none

Contacts and Locations
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Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04952246


Contacts
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Contact: Jian Li +86 13701023871 dsfan@sina.com

Locations
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China
Peking University Third Hospital Recruiting
Beijin, China
Contact: Dongsheng Fan    13701023871    dsfan@sina.com   
Sponsors and Collaborators
Peking University Third Hospital
Investigators
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Principal Investigator: Dongsheng Fan Peking University Third Hospital
More Information
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Responsible Party: Peking University Third Hospital
ClinicalTrials.gov Identifier: NCT04952246    
Other Study ID Numbers: M2020513
First Posted: July 7, 2021    Key Record Dates
Last Update Posted: July 7, 2021
Last Verified: June 2021

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Additional relevant MeSH terms:
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Multiple Sclerosis
Syndrome
Sclerosis
Disease
Pathologic Processes
Demyelinating Autoimmune Diseases, CNS
 Autoimmune Diseases of the Nervous System
Nervous System Diseases
Demyelinating Diseases
Autoimmune Diseases
Immune System Diseases