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Gender Differences in Parkinsonian Patients- a Swedish Register Study

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ClinicalTrials.gov Identifier: NCT04713306
Recruitment Status : Withdrawn
First Posted : January 19, 2021
Last Update Posted : January 19, 2021
Sponsor:
Collaborators:
Jonkoping University
Karolinska Institutet
Information provided by (Responsible Party):
Region Jönköping County

Brief Summary:
BACKGROUND: The complex impact of gender has been studied in different perspectives of health and disease in the literature. However, few attempts have been made to compile data from systematic disease specific registrations Swedish National Quality Registers play an important role in collecting large amounts of diagnose specific data, symptoms, and treatments. The subset Parkinson Registry has been in use for more than 20 years and are represented in all counties and hospitals where neurological care is provided in Sweden and offer optimal conditions to describe gender specific differences in the use of diagnostic tools, lead times and symptom profiles.

Condition or disease
Parkinson Disease

Detailed Description:

Aim: To study differences between gender in diagnostic tools, pharmacological interventions, and self-reported symptoms in Parkinson´s Disease (PD).

METHODS:

Data were extracted from the Swedish Neuro Registers, one of the Swedish National Quality Registers. A mix of urban and rural parts of the country were chosen and data were divided by gender. Self-reported first experienced PD related symptom was used to define the starting point when processing the data. Zero to three years from this point was defined as early symptoms and over three years as late symptoms.

CONCLUSION:

Differences between gender were seen in all chosen aspects, both diagnostically. Distinctions were also prominent in reported NonMotorSymptoms (NMS) profiles. These findings should be important to take into consideration for patients, professional staff, and caregivers in the daily work with gender mixed PD groups.

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Study Type : Observational [Patient Registry]
Actual Enrollment : 0 participants
Observational Model: Cohort
Time Perspective: Other
Target Follow-Up Duration: 14 Years
Official Title: Gender Differences in Diagnostic Tools, Medication, Time to Medication and Non-motor Symptoms in Parkinsonian Patients- a Swedish Register Study
Actual Study Start Date : January 1, 2006
Actual Primary Completion Date : May 1, 2019
Actual Study Completion Date : December 31, 2019

Resource links provided by the National Library of Medicine


Group/Cohort
Participants in the Swedish Neuro Register
Participants are patients with parkinsonian symptoms



Primary Outcome Measures :
  1. Differences between gender [ Time Frame: 2006-2020 ]
    investigations, medications,NonMotorSymptoms



Information from the National Library of Medicine

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Ages Eligible for Study:   1 Year to 100 Years   (Child, Adult, Older Adult)
Sexes Eligible for Study:   All
Gender Based Eligibility:   Yes
Gender Eligibility Description:   yes self-representation
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
Cohorts from rural areas and larger cities of Southern Sweden with diagnosed parkinsonism.
Criteria

Inclusion:

Participants registered in the Swedish Neuro Registers. Parkinson´s Disease Acceptance of extraction of data -

Exclusion Criteria:

non parkinsonian patients Participants in the Registries who have not given allowance of extraction of data.

-


Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04713306


Locations
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Sweden
FUTURUM
Jönköping, Sweden, SE 551 85
Sponsors and Collaborators
Region Jönköping County
Jonkoping University
Karolinska Institutet
Investigators
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Study Director: Johan Lokk, PhD Karolinska Institutet
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Responsible Party: Region Jönköping County
ClinicalTrials.gov Identifier: NCT04713306    
Other Study ID Numbers: XXXXX
First Posted: January 19, 2021    Key Record Dates
Last Update Posted: January 19, 2021
Last Verified: October 2020
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Keywords provided by Region Jönköping County:
NonMotorSymptoms (NMS), medication, investigation, National Registries
Additional relevant MeSH terms:
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Parkinson Disease
Parkinsonian Disorders
Basal Ganglia Diseases
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Movement Disorders
Neurodegenerative Diseases