Electrical Impedance Tomography: Collapse in Dependent Areas as a Predictor of Response to Prone Position Ventilation in COVID-19 Acute Respiratory Distress Syndrome (COVIDEIT)
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|ClinicalTrials.gov Identifier: NCT04603755|
Recruitment Status : Recruiting
First Posted : October 27, 2020
Last Update Posted : November 9, 2020
There are several clinical presentations of SARS-CoV-2 infection. Among the severe forms, pulmonary involvement with respiratory failure is common. Although severe lung involvement with SARS-CoV-2 meets the Berlin criteria for Acute Respiratory Distress Syndrome (ARDS), it differs from classic ARDS in that compliance (reflecting distensibility of the lung parenchyma) is frequently preserved.
If the interest of Electrical Impedance Tomography has been demonstrated in classical ARDS, this is not the case in ARDS with COVID-19.
However, the use of this technique in this particular patient population would make it possible to distinguish patients with severe hypoxemia linked to derecruitment from those without derecruitment, in whom hypoxemia is more likely to be linked to the loss of hypoxic vasoconstriction.
|Condition or disease||Intervention/treatment|
|SARS-CoV Infection Acute Respiratory Distress Syndrome||Device: Electrical Impedance tomography|
|Study Type :||Observational|
|Estimated Enrollment :||15 participants|
|Official Title:||Electrical Impedance Tomography: Collapse in Dependent Areas as a Predictor of Response to Prone Position Ventilation in COVID-19 Acute Respiratory Distress Syndrome|
|Actual Study Start Date :||October 26, 2020|
|Estimated Primary Completion Date :||April 2022|
|Estimated Study Completion Date :||April 2022|
- Device: Electrical Impedance tomography
Electrical Impedance tomography recording during 5 minutes every day during 7 days
- Coefficient of correlation between the percentage of derecruitment of dependent areas (measured with Electrical Impedance Tomography) and the response to prone position [ Time Frame: Up to 7 days ]
The percentage of derecruitment of dependent areas will be measured every day with Electrical Impedance Tomography.
The response to prone position will be assessed every day.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04603755
|Contact: Michael CARDINALE, MD||483162204 ext +firstname.lastname@example.org|
|Hôpital d'Instruction des Armées Sainte-Anne||Recruiting|
|Toulon, France, 83800|
|Contact: Michael CARDINALE, MD 483162204 ext +33 email@example.com|