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Factors Influencing the Deterioration From Cognitive Decline of Normal Aging to Dementia Among Nursing Home Residents

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ClinicalTrials.gov Identifier: NCT04589637
Recruitment Status : Completed
First Posted : October 19, 2020
Last Update Posted : October 19, 2020
Sponsor:
Information provided by (Responsible Party):
Jordan University of Science and Technology

Brief Summary:

Background: A dearth of differential research exists regarding the determinants of mild cognitive impairment (MCI) and moderate cognitive impairment or dementia among nursing home residents. This study aimed to identify and examine the association between medical factors (number of comorbidities, hospitalization, disability, depression, frailty and quality of life) and moderate cognitive impairment or dementia in nursing homes residents.

Methods: A cross-sectional design was used in this study. Convenience sampling of 182 participants was conducted in nursing homes located in the central part of Jordan. Montreal cognitive assessment (MoCA) was used to screen both MCI and moderate cognitive impairment or dementia. Bivariate analysis, including t-test and ANOVA test, and logistic and linear regression models were used to examine and identify the medical factors associated with moderate cognitive impairment or dementia compared to mild cognitive impairment.


Condition or disease
Dementia

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Study Type : Observational
Actual Enrollment : 182 participants
Observational Model: Cohort
Time Perspective: Cross-Sectional
Official Title: Factors Influencing the Deterioration From Cognitive Decline of Normal Aging to Dementia Among Nursing Home Residents
Actual Study Start Date : May 29, 2018
Actual Primary Completion Date : December 1, 2018
Actual Study Completion Date : May 16, 2019

Resource links provided by the National Library of Medicine





Primary Outcome Measures :
  1. moderate cognitive impairment [ Time Frame: May, 2018-May, 2019 ]


Information from the National Library of Medicine

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Ages Eligible for Study:   60 Years to 85 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Sampling Method:   Non-Probability Sample
Study Population
Convenience sampling of 182 participants was used to obtain moderate size correlation (r = 0.35), given a power of 0.80, two-sided Type I error rate of p = 0.0167, based on nQuery calculation [16]. The participants were recruited from 5 holistic nursing homes, including private and public nursing homes, located in the center of Jordan. Inclusion criteria were as follows: Jordanian participants, aged 60 years and older, and living in nursing homes. Exclusion criteria were neurological disorders, such as stroke or brain injury.
Criteria

Inclusion Criteria:

  • Jordanian participants, aged 60 years and older, and living in nursing homes

Exclusion Criteria:

  • neurological disorders, such as stroke or brain injury

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04589637


Locations
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Jordan
Nursing homes
Amman, Jordan
Sponsors and Collaborators
Jordan University of Science and Technology
Publications of Results:

Other Publications:
Kijowska, V., Szczerbińska, K. (2018). Prevalence of cognitive impairment among long-term care residents: a comparison between nursing homes and residential homes in Poland. Eur Geriatr Med 9, 467-476 https://doi.org/10.1007/s41999-018-0062-2
Hayajneh, A.A. , Ivanov, L.L. & Rababa, M. (2019). Jordanian Nursing Homes: Admission Policy Analysis. Global Journal of Health Science, 11 (6), 118-122.
Janet D. Elashoff. nQuery Advisor Version 7.0 [software]. 2007: User's Guide. Los Angeles, CA
The Montreal Cognitive Assessment (MoCA). What are the severity levels for the MoCA?. : Copyright 2019 Ziad Nasreddine MD. All rights reserved. Available from:: https://www.mocatest.org/faq/ [30August2020]
Greenberg, S. Try this: the Geriatric Depression Scale (GDS). 2012: 4. The Hartford Institute for Geriatric Nursing, New York University, College of Nursing.
Hayajneh, A. A. The Psychometric Properties of the Arabic Version of the Tilburg Frailty Indicator. Global Journal of Health Science. 2019: 11(9), 123-133. doi:10.5539/gjhs.v11n9p123
Al-btoush, A. Relation between the Psychological Impact of Presbycusis and Hearing Handicap Inventory for the Elderly Using Screening Version in Jordan. Middle East Journal of Age and Ageing. 2012: 9(5), 23-25.
Abdelmoneium, A.O. & Alharahsheh, S.T. Family Home Caregivers for Old Persons in the Arab Region: Perceived Challenges and Policy Implications. Open Journal of Social Sciences. 2016: 4, 151-164. http://dx.doi.org/10.4236/jss.2016.41019
Arafa, Mohamed A., What's New in the Residential Care of the Elderly in the Arab and Islamic World? The Case of Egypt. Towards Human Rights in Residential Care for Older Persons: International Perspectives. 2015: (Chapter 2, Routledge, London & New York), Available at SSRN: https://ssrn.com/abstract=2710357
Atif, M., Saleem, Q. & Scahill, S. Depression and mild cognitive impairment (MCI) among elderly patients with type 2 diabetes mellitus in Pakistan: possible determinants. Int J Diabetes Dev Ctries. 2018: 38, 312-320. https://doi.org/10.1007/s13410-017-0600-3
Elliott, I. Poverty and Mental Health: A review to inform the Joseph Rowntree Foundation's Anti-Poverty Strategy. 2016: London: Mental Health Foundation.
Mosti C.B., Rog L.A., Fink J.W. Differentiating Mild Cognitive Impairment and Cognitive Changes of Normal Aging. In: Ravdin L., Katzen H. (eds) Handbook on the Neuropsychology of Aging and Dementia. Clinical Handbooks in Neuropsychology. 2019. Springer, Cham

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
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Responsible Party: Jordan University of Science and Technology
ClinicalTrials.gov Identifier: NCT04589637    
Other Study ID Numbers: JUST20180229
First Posted: October 19, 2020    Key Record Dates
Last Update Posted: October 19, 2020
Last Verified: October 2020
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Additional relevant MeSH terms:
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Dementia
Cognitive Dysfunction
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Neurocognitive Disorders
Mental Disorders
Cognition Disorders