Working…
COVID-19 is an emerging, rapidly evolving situation.
Get the latest public health information from CDC: https://www.coronavirus.gov.

Get the latest research information from NIH: https://www.nih.gov/coronavirus.
ClinicalTrials.gov
ClinicalTrials.gov Menu

Influence of Obuvacaine Hydrochloride Eye Drops on the Comfort of Meibomian Gland Massage Patients

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT04569422
Recruitment Status : Recruiting
First Posted : September 29, 2020
Last Update Posted : September 29, 2020
Sponsor:
Information provided by (Responsible Party):
JJiang Junyi, Aier School of Ophthalmology, Central South University

Brief Summary:
In this study, there were differences in patients' demands for ephedrine during meibomian gland massage and whether it would affect patients' poor comfort. Therefore, we needed to collect patients' pain grades during meibomian gland massage

Condition or disease Intervention/treatment
Meibomian Gland Massage is Important to Delay the Development of Meibomian Gland Dysfunction Drug: Benoxyl

Detailed Description:

Meibomian gland dysfunction is a common eye disease that may be asymptomatic or painful and itchy in the early stages, requiring early daily care and medication. And meibomian gland massage is a very important step in the treatment. Meibomian gland massage is massaging along the direction of meibomian gland drainage to push out secretions that cannot be discharged by themselves, improve meibomian gland function, and delay the development of meibomian gland dysfunction.Meibomian gland dysfunction is a common eye disease that may be asymptomatic or painful and itchy in the early stages, requiring early daily care and medication. And meibomian gland massage is a very important step in the treatment. Meibomian gland massage is massaging along the direction of meibomian gland drainage to push out secretions that cannot be discharged by themselves, improve meibomian gland function, and delay the development of meibomian gland dysfunction.Meibomian gland dysfunction is a common eye disease that may be asymptomatic or painful and itchy in the early stages, requiring early daily care and medication. And meibomian gland massage is a very important step in the treatment. Meibomian gland massage is massaging along the direction of meibomian gland drainage to push out secretions that cannot be discharged by themselves, improve meibomian gland function, and delay the development of meibomian gland dysfunction.

Methods: We selected dry eye patients who visited dry eye clinic of Aier Eye Hospital from June 2020 to March 2021 to conduct questionnaire survey and analysis with pain scaleMethods: We selected dry eye patients who visited dry eye clinic of Aier Eye Hospital from June 2020 to March 2021 to conduct questionnaire survey and analysis with pain scale Group: Divided into ephedrine drop group and artificial tear drop group Research tool: Pain rating scale

Layout table for study information
Study Type : Observational
Estimated Enrollment : 100 participants
Observational Model: Case-Control
Time Perspective: Prospective
Official Title: Influence of Obuvacaine Hydrochloride Eye Drops on the Comfort of Meibomian Gland Massage Patients
Actual Study Start Date : June 1, 2020
Estimated Primary Completion Date : March 21, 2021
Estimated Study Completion Date : May 21, 2021

Resource links provided by the National Library of Medicine


Group/Cohort Intervention/treatment
ephedrine drop Drug: Benoxyl
reduce pain




Primary Outcome Measures :
  1. Undifferrentiated [ Time Frame: 2020.01-2020.09 ]
    There was no difference in the effect of obuvacaine hydrochloride on the comfort of meibomian gland massage patients



Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Layout table for eligibility information
Ages Eligible for Study:   18 Years to 80 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
Meibomian gland dysfunction people with no chronic disease
Criteria

Inclusion Criteria:

Healthy people with no chronic disease

Exclusion Criteria:

People with chronic disease


Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04569422


Contacts
Layout table for location contacts
Contact: Yuanyuan Yin, bachelor 18621755180 815969138@qq.com

Locations
Layout table for location information
China, Hunan
Aier School of Ophthalmology, Central South University Recruiting
Changsha, Hunan, China
Contact: Shibo Tang, Prof    00-86-0755-23809666    tangshibo@vip.163.com   
Sponsors and Collaborators
Aier School of Ophthalmology, Central South University
Investigators
Layout table for investigator information
Principal Investigator: Yuanyuan Yin, bachelor Shanghai Aier Eye Hospital
Layout table for additonal information
Responsible Party: JJiang Junyi, Influence of Obuvacaine Hydrochloride Eye Drops on the Comfort of Meibomian Gland Massage Patients, Aier School of Ophthalmology, Central South University
ClinicalTrials.gov Identifier: NCT04569422    
Other Study ID Numbers: 2020-002-01
First Posted: September 29, 2020    Key Record Dates
Last Update Posted: September 29, 2020
Last Verified: September 2020

Layout table for additional information
Studies a U.S. FDA-regulated Drug Product: Yes
Studies a U.S. FDA-regulated Device Product: No
Product Manufactured in and Exported from the U.S.: Yes
Additional relevant MeSH terms:
Layout table for MeSH terms
Benzoyl Peroxide
Dermatologic Agents