Comparisons of gaIt aNalyses pERformance Between the Gaitrite walkwaYs (CINERGY)
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT04557592|
Recruitment Status : Completed
First Posted : September 21, 2020
Last Update Posted : September 21, 2020
The GAITRite® system is an instrumented with resistive pressure sensors gait analyzer. It was first validate in 2001 against paper-and-pencil (intraclass correlation coefficient [ICC] > 95%) for spatial measures and against video-based (ICC > 93%) for temporal measures, and was thus a reliable tools to measure step lengths and times in both walkway center and left-of-center measurements. It was considered as one of the gold standards in gait analyses. This gait analyze system may distinguish prospectively faller and non-faller older adults, but it can detect spatial, temporal, and spatiotemporal measures of gait and greater variability of gait parameters which were associated with and predictive of both global- and domain-specific cognitive decline. Moreover, spatiotemporal gait parameters analyzed using GAITRite® were more disturbed in the advanced stages of dementia, and more affected in the non-AD dementia than in AD suggesting that quantitative gait parameters could be used as a surrogate marker for improving the diagnosis of dementia.
Nevertheless, GAITRite® is not a unique system and it comprises different walkways. One of these technologies was a roll-up system (platinum plus classic, RE, Basic and Safari), and the other was a system composed by a changeable association of plates (CIRFACE). In order to ensure a good comparability between studies using these different walkways, it appears important to compare the performances of these walkways in gait analysis. Thus, the main aim of this study was to compare the performances in gait analyze between the GAITRite® platinum plus classic and the GAITRite® CIRFACE among older adults. Secondary aims were to compare these parameters among patients with cognitive complaint, minor or major neurocognitive disorder (NCD) related to Alzheimer disease.
|Condition or disease|
|Gait Apraxia Alzheimer Disease Impaired Cognition|
|Study Type :||Observational|
|Actual Enrollment :||98 participants|
|Official Title:||Comparisons of gaIt aNalyses pERformance Between the Gaitrite walkwaYs|
|Actual Study Start Date :||June 17, 2019|
|Actual Primary Completion Date :||February 26, 2020|
|Actual Study Completion Date :||February 26, 2020|
- Change in spatiotemporal gait, and in particular in the variability of stride time between the two devices [ Time Frame: baseline ]in the sub-group: Absence of cognitive impairment
- Change in spatiotemporal gait, and in particular in the variability of stride time between the two devices [ Time Frame: baseline ]in the sub-group: Minor Neurocognitive Disorder
- Change in spatiotemporal gait, and in particular in the variability of stride time between the two devices [ Time Frame: baseline ]in the sub-group: Major Neurocognitive Disorder
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04557592
|Angers University Hospital|
|Angers, France, 49933|