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Age-related Changes of Crystalline Lens Tilt and Decentration: A Swept-source Optical Coherence Tomography Study

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT04487795
Recruitment Status : Completed
First Posted : July 27, 2020
Last Update Posted : July 27, 2020
Sponsor:
Information provided by (Responsible Party):
Yune Zhao, Wenzhou Medical University

Brief Summary:
230 participants at Eye Hospital of Wenzhou Medical University during June, 2019 and August, 2019 were enrolled in this study. 230 right eyes and 88 left eyes were included for the measurement. All the measurements were performed under non-mydriatic conditions in a dim examination room using the CASIA2 swept-source AS-OCT system.

Condition or disease
Crystalline Cataract Lens; Anomaly

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Study Type : Observational
Actual Enrollment : 230 participants
Observational Model: Case-Only
Time Perspective: Retrospective
Official Title: Age-related Changes of Crystalline Lens Tilt and Decentration: A Swept-source Optical Coherence Tomography Study
Actual Study Start Date : April 15, 2020
Actual Primary Completion Date : April 30, 2020
Actual Study Completion Date : May 17, 2020

Group/Cohort
under 18 years old
18-40 years old
41-60 years old
over 60 years old



Primary Outcome Measures :
  1. crystalline lens tilt [ Time Frame: 2020.4.30 ]
    magnitude and direction of crystalline lens lilt

  2. crystalline lens decentration [ Time Frame: 2020.4.30 ]
    magnitude and direction of crystalline lens decentration



Information from the National Library of Medicine

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Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
Healthy volunteers and patients with age-related cataract at Eye hospital of Wenzhou Medical University
Criteria

Inclusion Criteria:

  • healthy volunteers and patients with age-related cataract

Exclusion Criteria:

  • aphakia or pseudophakia
  • any other ocular diseases with the exception of senile cataract
  • any history of ocular surgery
  • fixation difficulties caused by any reasons

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04487795


Locations
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China, Zhejiang
Ophthalmology and Optometry Hospital
Wenzhou, Zhejiang, China, 325027
Sponsors and Collaborators
Yune Zhao
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Responsible Party: Yune Zhao, Vice president of Eye Hospital of Wenzhou Medical University, Wenzhou Medical University
ClinicalTrials.gov Identifier: NCT04487795    
Other Study ID Numbers: SSOCT-lens tilt
First Posted: July 27, 2020    Key Record Dates
Last Update Posted: July 27, 2020
Last Verified: July 2020

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Keywords provided by Yune Zhao, Wenzhou Medical University:
crystalline lens tilt
crystalline lens decentration
swept-source optical coherence tomography
Additional relevant MeSH terms:
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Cataract
Lens Diseases
Eye Diseases