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Do Childhood Measles and DTaP Vaccination Decrease the Mortality Rate Caused by COVID-19 in OECD Countries?

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ClinicalTrials.gov Identifier: NCT04468802
Recruitment Status : Completed
First Posted : July 13, 2020
Last Update Posted : July 14, 2020
Sponsor:
Information provided by (Responsible Party):
Ramazan Guven, Kanuni Sultan Suleyman Training and Research Hospital

Brief Summary:
Mortality rates caused by SARS CoV-2 differ between countries and this difference might be explained by several reasons. Childhood vaccination rate is thought to be one of them. Therefore present study aimed to examine the possible relationship between DTaP (diphtheria, tetanus, pertussis) and measles vaccination rates of Organization for Economic Co-operation and Development (OECD) countries and case fatality rate (CFR) caused by SARS CoV-2.

Condition or disease Intervention/treatment
Covid19 Measles Vaccine Mortality Other: Case fatality rate

Detailed Description:
The mortality rates caused by SARS CoV-2 differ between countries and this difference might be explained by several reasons. Childhood vaccination rate is thought to be one of them. Therefore present study aimed to examine the possible relationship between DTaP (diphtheria, tetanus, pertussis) and measles vaccination rates of Organization for Economic Co-operation and Development (OECD) countries and case fatality rate (CFR) caused by SARS CoV-2.A total of 32 OECD countries, of northern hemisphere, have been included in this study. Statistical analysis performed according to the CFR data of these countries based on SARS CoV-2. The CFR data calculated according to the total mortality count of a specific country for the 3-month period down from the date when first SARS CoV-2 case was observed.

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Study Type : Observational
Actual Enrollment : 32 participants
Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Do Childhood Measles and DTaP Vaccination Decrease the Mortality Rate Caused by SARS CoV-2 in OECD Countries?
Actual Study Start Date : February 1, 2020
Actual Primary Completion Date : June 30, 2020
Actual Study Completion Date : July 1, 2020

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Measles


Intervention Details:
  • Other: Case fatality rate
    Mortality rate caused by SARS CoV-2


Primary Outcome Measures :
  1. Case Fatality Rate [ Time Frame: 4 months ]
    Mortality rate caused by SARS CoV-2



Information from the National Library of Medicine

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Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
Children vaccinated in OECD countries in northern hemisphere
Criteria

Inclusion Criteria:

  • Children vaccinated in OECD countries in northern hemisphere

Exclusion Criteria:

  • Non vaccinated children
  • Southern hemisphere countries
  • non-OECD countries

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04468802


Locations
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Turkey
Istanbul Kanuni Sultan Suleyman Training and Research Hospital
Istanbul, Kucukcekmece, Turkey, 34303
Sponsors and Collaborators
Kanuni Sultan Suleyman Training and Research Hospital
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Responsible Party: Ramazan Guven, Professor, Kanuni Sultan Suleyman Training and Research Hospital
ClinicalTrials.gov Identifier: NCT04468802    
Other Study ID Numbers: KSSEAH--0965
First Posted: July 13, 2020    Key Record Dates
Last Update Posted: July 14, 2020
Last Verified: July 2020
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: Undecided

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Additional relevant MeSH terms:
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Measles
Morbillivirus Infections
Paramyxoviridae Infections
Mononegavirales Infections
RNA Virus Infections
Virus Diseases