VR Motor-cognitive Training for Cognitive Frailty
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|ClinicalTrials.gov Identifier: NCT04467216|
Recruitment Status : Not yet recruiting
First Posted : July 10, 2020
Last Update Posted : July 10, 2020
Cognitive frailty is a clinical syndrome in which cognitive impairment (e.g., poor memory, visuospatial function) and physical frailty (e.g., slowness, poor muscle strength, physical inactivity) co-exist. It is prevalent in community-dwelling older people. The progressive decline of cognitive and physical functions restricts older people from participating in activities (e.g., social get-togethers). Reduced participation further jeopardizes their life-space mobility (e.g., ability to travel to areas far away from home). Therefore, those with cognitive frailty are at risk of developing dementia and becoming dependent.
Simultaneous motor-cognitive training is more effective at promoting optimal functioning in older people than motor or cognitive training alone. Gaming is effective at promoting the motivation to participate. The contents of games in the market are unrelated to the context or daily living of the elderly. Currently, available training is non-simultaneous. This makes the training less transferable to the daily life of the elderly and reduces its effects.
Virtual reality (VR) technology can provide a virtual space that mimics the real environment. This allows clients to participate in daily activities in a virtual space. Older people can be trained to improve their cognitive and physical skills in a painless, fun way. However, the effect and feasibility of employing simultaneous motor-cognitive training launching on a VR platform mimicking the daily living environment in older people with cognitive frailty is poorly known. This pilot trial aims to examine the preliminary effects on cognitive function and frailty syndrome, as well as examine the feasibility.
|Condition or disease||Intervention/treatment||Phase|
|Cognitive Frailty||Device: Computerised cognitive training using virtual reality||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||16 participants|
|Intervention Model:||Parallel Assignment|
|Intervention Model Description:||
A total of 16 subjects with cognitive frailty will be assigned into 2 groups. Eight participants will be assigned to the intervention group in which they will undertake VR simultaneous motor-cognitive training and eight participants will be assigned to the control group in which existing forms of non-VR sequential motor-cognitive training will be provided.
Both intervention and control groups will employ the same intervention dosage including course, session duration and frequency. The following dosage is employed because they are also the same dosage used in the VR simultaneous motor-cognitive training that we proposed. I.e.,
|Masking:||Single (Outcomes Assessor)|
|Masking Description:||Outcome assessors at both pre- and post-observations will be blinded to the group label|
|Official Title:||Virtual Reality Motor-cognitive Training for Older People With Cognitive Frailty: A Pilot Trial|
|Estimated Study Start Date :||July 15, 2020|
|Estimated Primary Completion Date :||October 30, 2020|
|Estimated Study Completion Date :||December 31, 2020|
Experimental: Intervention group
This arm will undertake VR simultaneous motor-cognitive training in 30 minutes session, twice a week for 8 weeks
Device: Computerised cognitive training using virtual reality
Immersive VR training system tailor-made for the daily living experiences in the Hong Kong context to provide interactive experiences for older people in Hong Kong.The VR systems available in the market for older people are only for non-interactive activities (e.g., watching movies) to provide unusual experiences for disabled older people who cannot travel too far from home.
No Intervention: Control Group
This arm will be doing existing forms of motor-cognitive training in 30 minutes session, twice a week for 8 weeks
- Global cognitive function [ Time Frame: Change is being assessed: "baseline" and "immediately after the completion" (2 months) ]MoCA (score)
- Selective attention [ Time Frame: Change is being assessed: "baseline" and "immediately after the completion" (2 months) ]Stroop test (score)
- Visual-spatial perception [ Time Frame: Change is being assessed: "baseline" and "immediately after the completion" (2 months) ]Visual Object Space Perception test (score)
- Frailty [ Time Frame: Change is being assessed: "baseline" and "immediately after the completion" (2 months) ]Fried Frailty Phenotype (score)
- Walking [ Time Frame: Change is being assessed: "baseline" and "immediately after the completion" (2 months) ]Timed up and go test (seconds)
- Strength [ Time Frame: Change is being assessed: "baseline" and "immediately after the completion" (2 months) ]Grip strength by dynamometer (kg)
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04467216
|Contact: Rick Kwan||96690420 ext firstname.lastname@example.org|
|Pok Oi Hospital Neighbourhood Elderly Centre|
|Hong Kong, Hong Kong|
|Contact: Olive Sin 98519917 email@example.com|
|Study Chair:||Rick Kwan||The Hong Kong Polytechnic University|