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Outcomes in Hospitalized Older Patients With COVID-19

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT04385212
Recruitment Status : Completed
First Posted : May 12, 2020
Last Update Posted : May 12, 2020
Sponsor:
Information provided by (Responsible Party):
Christine Serratrice, MD, University Hospital, Geneva

Brief Summary:
In December 2019, the first patients infected with the 2019 novel coronavirus (2019-nCoV) were diagnosed in Wuhan. The clinical presentation and course of Severe Acute Respiratory Syndrome-CoV-2 (SARS-CoV-2) infection is poorly understood in older patients and is certainly different from the general population. This project is designed to better understand and to determine clinical, biological and radiological markers of poor adverse outcomes in hospitalized older patients diagnosed with COVID-19.

Condition or disease
Coronavirus Infection Sars-CoV2 Elderly Infection Old Age; Debility

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Study Type : Observational
Actual Enrollment : 230 participants
Observational Model: Cohort
Time Perspective: Retrospective
Official Title: COVIDAge Study- Hospital Des Trois-Chêne
Actual Study Start Date : March 13, 2020
Actual Primary Completion Date : April 14, 2020
Actual Study Completion Date : April 14, 2020

Resource links provided by the National Library of Medicine





Primary Outcome Measures :
  1. To evaluate the relative contributions of comorbidities on intra-hospitalized death [ Time Frame: 1 month ]
    We measure functional score of comorbidities


Secondary Outcome Measures :
  1. To evaluate the relative contributions of functional characteristics on intra-hospitalized death [ Time Frame: 1 month ]
    We measure Functional Independence Measure scale

  2. To explore specific clinical profiles that may influence COVID-19 disease outcomes in the elderly based on geriatrics syndromes [ Time Frame: 1 month ]
    We describe the role fo geriatric syndrome such as delirium, falls



Information from the National Library of Medicine

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Ages Eligible for Study:   65 Years and older   (Older Adult)
Sexes Eligible for Study:   All
Sampling Method:   Non-Probability Sample
Study Population
All the patients hospitalized in our geriatrics department with Sars-Cov-2 infection
Criteria

Inclusion Criteria:

  • Diagnosis of COVID-19, defined by a positive polymerase chain reaction (PCR) test for SARS-CoV-2 detection, obtained by a nasopharyngeal swab or sputum sample.
  • Or patients with negative virus detection in the PCR test, but with a high clinical suspicion will also be considered with COVID-19.

Exclusion Criteria:

- Presence of document indicating a refusal to participate in a research study.


Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04385212


Locations
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Switzerland
Department of Rehabilitation and Geriatrics
Geneva, Switzerland, 1256
Sponsors and Collaborators
University Hospital, Geneva
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Responsible Party: Christine Serratrice, MD, Principal Investigator, University Hospital, Geneva
ClinicalTrials.gov Identifier: NCT04385212    
Other Study ID Numbers: 2020-00819
First Posted: May 12, 2020    Key Record Dates
Last Update Posted: May 12, 2020
Last Verified: May 2020
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: Undecided

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Additional relevant MeSH terms:
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Infection
Communicable Diseases
Coronavirus Infections
Severe Acute Respiratory Syndrome
Coronaviridae Infections
Nidovirales Infections
RNA Virus Infections
Virus Diseases
Respiratory Tract Infections
Respiratory Tract Diseases