Prono Position and Mechanical Power (PROMP)
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|ClinicalTrials.gov Identifier: NCT04369105|
Recruitment Status : Recruiting
First Posted : April 30, 2020
Last Update Posted : August 26, 2020
The primary objective of the study is to compare the mechanical power applied to the respiratory system in patient with acute respiratory distress syndrome in supine positioning and after the implementation of prone positioning while mantaining the same ventilatory setting.
The secondary objetive of the study is to compare the mechanical power applied to the respiratory system in patient with acute respiratory distress syndrome in supine positioning and after the implementation of prone positioning and adjusting an individualized ventilatory setting.
|Condition or disease||Intervention/treatment|
|Acute Respiratory Distress Syndrome||Other: Prone position|
Data of mechanical power will be collected prospectively in three different times:
- In supine positioning (T0).
- After 15 minutes of having implemented prone positioning while maintaining the same ventilatory settings that in supine (T1).
- In prone positioning after 15 min of having adjusted an individualized ventilatory setting (T2).
Besides, the investigators will take an arterial blood sample in T0 and T2 to calculate changes in oxygenation status and ventilatory ratio.
In case that esophageal manometry is available, the investigators will collect data regarding to transpulmonary and esophageal pressure in order to calculate the mechanical power applied to the lung parenchyma.
|Study Type :||Observational|
|Estimated Enrollment :||20 participants|
|Official Title:||Influence of the Prone Position on Mechanical Power Applied to Respiratory System: Multi-centric Descriptive Study|
|Actual Study Start Date :||May 1, 2020|
|Estimated Primary Completion Date :||October 31, 2020|
|Estimated Study Completion Date :||November 30, 2020|
- Other: Prone position
The patients will be put in prone position while receiving invasive mechanical ventilation and the investigators will monitor changes in mechanical power applied to the respiratory system and compare with supine position
- Mechanical power of the respiratory system measured in supine compared with prone position while maintaining the same ventilatory setting [ Time Frame: 1) Supine position; 2) Prone position, after 15 min ]Mechanical power measured in Joules/min
- Mechanical power of the respiratory system measured in supine compared with prone position after adjusting the ventilatory setting [ Time Frame: 1) Supine position; 2) Prone position, after 15 min of adjusting ventilatory setting. ]Mechanical power measured in Joules/min
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04369105
|Contact: matias accoce, Physiotherapyfirstname.lastname@example.org|
|Contact: Joaquin Pérez, Physiotherapyemail@example.com|