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Observing the Morphology of Schlemm's Canal and Crystalline Lens in Different Age

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT04360161
Recruitment Status : Completed
First Posted : April 24, 2020
Last Update Posted : April 24, 2020
Sponsor:
Information provided by (Responsible Party):
Yune Zhao, Wenzhou Medical University

Brief Summary:
The aim of this study is to quantify and observe the morphology of trabecular meshwork (TM), Schlemm's canal (SC), ciliary body and crystalline lens before and after cycloplegia in patients with different ages using swept-source optical coherence tomography.

Condition or disease Intervention/treatment Phase
Schlemm's Canal Occlusion Device: swept-source optical coherence tomography Not Applicable

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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 80 participants
Allocation: N/A
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Prevention
Official Title: Morphology of Schlemm's Canal and Crystalline Lens in Different Age: a Swept-source Optical Coherence Tomography Study
Actual Study Start Date : August 8, 2019
Actual Primary Completion Date : December 20, 2019
Actual Study Completion Date : January 20, 2020

Arm Intervention/treatment
Experimental: Healthy participants
Swept-source optical coherence tomography A device testing TM/SC and Lens morphology
Device: swept-source optical coherence tomography
Aswe pt-source OCT (CASIA SS-1000; Tomey Corporation, Nagoya, Japan), which is specifically designed for anterior segment imaging using a 1310 nm wavelength with a scan speed of 30,000 A-scans per second and an axial resolution of <10 μm.




Primary Outcome Measures :
  1. area of Schlemm's canal and trabecular meshwork [ Time Frame: up to 6 months ]
    The area of Schlemm's canal and trabecular meshwork was manually measured and the relationship between the parameters and age was analyzed.



Information from the National Library of Medicine

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Ages Eligible for Study:   7 Years to 60 Years   (Child, Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • healthy patients who can cooperated with the swept-source OCT measurements

Exclusion Criteria:

  • history of ocular disease
  • presence of central nervous system or systemic disease

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04360161


Locations
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China, Zhejiang
Eye Hospital of WMU
Hangzhou, Zhejiang, China, 325027
Sponsors and Collaborators
Wenzhou Medical University
Investigators
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Study Director: Yune Zhao Eye Hospital of Wenzhou Medical University
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Responsible Party: Yune Zhao, Director of Cataract Department, Wenzhou Medical University
ClinicalTrials.gov Identifier: NCT04360161    
Other Study ID Numbers: TM/SC/Lens-LZL
First Posted: April 24, 2020    Key Record Dates
Last Update Posted: April 24, 2020
Last Verified: April 2020
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No