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The Efficacy of Ivermectin and Nitazoxanide in COVID-19 Treatment

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ClinicalTrials.gov Identifier: NCT04351347
Recruitment Status : Recruiting
First Posted : April 17, 2020
Last Update Posted : December 17, 2020
Sponsor:
Information provided by (Responsible Party):
Sherief Abd-Elsalam, Tanta University

Study Description
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Brief Summary:
Efficacy of Ivermectin and Nitazoxanide in COVID-19 treatment

Condition or disease Intervention/treatment Phase
COVID Drug: Ivermectin Drug: Nitazoxanide with ivermectin Phase 2 Phase 3

Detailed Description:
Clinical Study Evaluating the Efficacy of Ivermectin and Nitazoxanide in COVID-19 treatment
Study Design
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Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 300 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Clinical Study Evaluating the Efficacy of Ivermectin and Nitazoxanide in COVID-19 Treatment
Actual Study Start Date : June 16, 2020
Estimated Primary Completion Date : December 1, 2030
Estimated Study Completion Date : December 1, 2030

Resource links provided by the National Library of Medicine


Arms and Interventions
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Arm Intervention/treatment
Experimental: Ivermectin
Ivermectin alone
 Drug: Ivermectin
ivermectin
Experimental: Nitazoxanide with Ivermectin
Nitazoxanide with Ivermectin
 Drug: Nitazoxanide with ivermectin
Nitazoxanide with ivermectin
Other Name: Alenia
No Intervention: Standard treatment
Standard of care treatment


Outcome Measures
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Primary Outcome Measures :
  1. Number of patients with improvement or died [ Time Frame: 1 month ]
    The number of patients with improvement or death


Eligibility Criteria
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Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Patients with covid 19

Exclusion Criteria:

  • Allergy or side effects to treatment
Contacts and Locations
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Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04351347


Contacts
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Contact: Sherief Abd-Elsalam, ass. prof. 00201147773440 sheriefabdelsalam@yahoo.com

Locations
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Egypt
Tanta University Recruiting
Tanta, Egypt, 35111
Contact: Sherief Abd-Elsalam         
Sponsors and Collaborators
Tanta University
Investigators
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Principal Investigator: sherief Abd-Elsalam, Ass. Prof. Tanta University - Faculty of Medicine
More Information
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Responsible Party: Sherief Abd-Elsalam, Ass. Prof. Tropical Medicine, Tanta University
ClinicalTrials.gov Identifier: NCT04351347    
Other Study ID Numbers: ivermecin covid
First Posted: April 17, 2020    Key Record Dates
Last Update Posted: December 17, 2020
Last Verified: December 2020
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Additional relevant MeSH terms:
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Ivermectin
Nitazoxanide
Antiparasitic Agents
Anti-Infective Agents