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Trial record 3 of 7 for:    jonatan ruiz

Caffeine Increases Maximal Fat Oxidation During Exercise in Endurance-trained Men: is There a Diurnal Variation

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ClinicalTrials.gov Identifier: NCT04320446
Recruitment Status : Completed
First Posted : March 25, 2020
Last Update Posted : March 25, 2020
Sponsor:
Information provided by (Responsible Party):
Jonatan Ruiz Ruiz, Universidad de Granada

Brief Summary:

Maximal fat oxidation during exercise (MFO) and the intensity of exercise that elicits MFO (Fatmax) has been recognized as potential determinants of endurance performance.

The purpose of this study was to determine the possible interaction between the effects of diurnal variation (morning vs. afternoon) and caffeine ingestion on MFO, Fatmax and VO2 max in endurance-trained men. Specifically, the investigators sought to elucidate whether the stimulant actions of caffeine could reverse the decrements of MFO and Fatmax observed in the morning.


Condition or disease Intervention/treatment Phase
Energy Metabolism Athletic Performance Behavioral: Test in the morning Behavioral: Test in the afternoon Not Applicable

Detailed Description:

Body weight, height, body composition (DXA), exercise test (MFO and VO2max assessment) will be measured during the 4 evaluations.

Participants were randomized into 4 exercise test conditions:

  1. Exercise test in the morning with placebo intake
  2. Exercise test in the evening with placebo intake
  3. Exercise test in the morning with caffeine intake
  4. Execrise test in the evening with caffeine intake

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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 15 participants
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Triple (Participant, Investigator, Outcomes Assessor)
Primary Purpose: Other
Official Title: Caffeine Increases Maximal Fat Oxidation During Exercise in Endurance-trained Men: is There a Diurnal Variation
Actual Study Start Date : June 1, 2019
Actual Primary Completion Date : November 30, 2019
Actual Study Completion Date : November 30, 2019

Resource links provided by the National Library of Medicine


Arm Intervention/treatment
Experimental: Caffeine
A dose of 3 mg/kg of caffeine (i.e. a vegetable extraction from green coffee beans, Harrison Sport Nutrition®, Spain) was ingested before the beginning of each test.
Behavioral: Test in the morning
The exercise test was performed between 8 a.m and 11 a.m
Other Name: MFO-morning, Fatmax-morning, and VO2max-morning

Behavioral: Test in the afternoon
The exercise test was performed between 5 p.m. and 8 p.m.a
Other Name: (MFO-afternoon, Fatmax-afternoon, and VO2max-afternoon

Placebo Comparator: Placebo
A dose of 3 mg/kg of placebo (i.e. 100% purity microcrystalline cellulose, Acofarma, Spain) was ingested before the beginning of each test.
Behavioral: Test in the morning
The exercise test was performed between 8 a.m and 11 a.m
Other Name: MFO-morning, Fatmax-morning, and VO2max-morning

Behavioral: Test in the afternoon
The exercise test was performed between 5 p.m. and 8 p.m.a
Other Name: (MFO-afternoon, Fatmax-afternoon, and VO2max-afternoon




Primary Outcome Measures :
  1. MFO [ Time Frame: Through study completion, an average of 1 month ]
    Maximal fat oxidation during exercise


Secondary Outcome Measures :
  1. FATmax [ Time Frame: Through study completion, an average of 1 month ]
    The intensity of exercise that elicits MFO

  2. VO2max [ Time Frame: Through study completion, an average of 1 month ]
    Cardiorrespiratory fitness measured by maximal oxygen uptake



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Ages Eligible for Study:   18 Years to 40 Years   (Adult)
Sexes Eligible for Study:   Male
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Having a body mass index (BMI) ranged from 18.5 to 28 kg/m2
  • not suffering any specific disease which can be aggravated by physical exercise
  • having previous experience in endurance training (i.e. self-reporting at least 2 years of cycling or running training including more than 3 training sessions/week).
  • Participant must be capable and willing to provide consent, understand exclusion criteria, instructions and protocols.

Exclusion Criteria:

  • Being smoker
  • Taking medication or drugs
  • Any non-controlled medical condition which could influence results or could be worsened by the participation in the study
  • Are deemed unsuitable by the investigator for any other reason, that prevent data collection.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04320446


Locations
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Spain
Instituto Mixto Universitario Deporte Salud
Granada, Spain, 18016
Sponsors and Collaborators
Universidad de Granada
Investigators
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Principal Investigator: Jonatan Ruiz Ruiz, Dr. Universidad de Granada
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
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Responsible Party: Jonatan Ruiz Ruiz, Associate professor, Universidad de Granada
ClinicalTrials.gov Identifier: NCT04320446    
Other Study ID Numbers: Nº 507/CEIH/2018
First Posted: March 25, 2020    Key Record Dates
Last Update Posted: March 25, 2020
Last Verified: March 2020
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Product Manufactured in and Exported from the U.S.: No