Hypercapnic Acute Respiratory Failure in the ICU : the YETI Study (YETI)
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|ClinicalTrials.gov Identifier: NCT04304339|
Recruitment Status : Suspended (Covid19 pandemia)
First Posted : March 11, 2020
Last Update Posted : November 19, 2020
Hypercapnia is a frequent clinical situation defined as an elevation of the partial pressure of carbon dioxide (PaCO2) above 45 mmHg. Several physiopathological parameters such as respiratory minute volume, dead space volume or CO2 production influence the PaCO2. Therefore, hypercapnia can affect the time of various diseases.
Available epidemiological data regarding hypercapnia are from studies investigating the efficacy of non-invasive ventilation (NIV), with different population cohorts. However, their interpretation must be cautious given the heterogeneity in patient case-mix and results.
Then, whether hypercapnia is a common reason for intensive care unit (ICU) admission, epidemiological data is scarce and heterogeneous. The aim of this study is to investigate the epidemiological, clinical determinants and outcomes of patients admitted to ICU with hypercapnic respiratory failure.
|Condition or disease||Intervention/treatment|
|Intensive Care Unit Syndrome Hypercapnia Acute Respiratory Failure||Other: Hypercapnic respiratory failure|
|Study Type :||Observational|
|Estimated Enrollment :||500 participants|
|Official Title:||Hypercapnic Acute Respiratory Failure in the ICU : the YETI Study|
|Actual Study Start Date :||September 22, 2020|
|Estimated Primary Completion Date :||September 1, 2021|
|Estimated Study Completion Date :||November 1, 2021|
- Other: Hypercapnic respiratory failure
Patients with hypercapnic respiratory failure will be followed without any additional intervention
- Prevalence of hypercapnic acute respiratory failure in ICU [ Time Frame: Intensive Care Unit length stay (Usually 7 days) ]Number of patients with hypercapnic acute respiratory failure in ICU related to number of patients admitted in the ICU during study period
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04304339
|CH Andre Migniot|
|Versailles, A, France|