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Endoscopic Findings of Gastritis in Children

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ClinicalTrials.gov Identifier: NCT04289519
Recruitment Status : Unknown
Verified February 2020 by HM Reyad, Assiut University.
Recruitment status was:  Not yet recruiting
First Posted : February 28, 2020
Last Update Posted : February 28, 2020
Information provided by (Responsible Party):
HM Reyad, Assiut University

Brief Summary:
Gastritis defines any (histologically confirmed) inflammation of the gastric mucosa

Condition or disease

Detailed Description:

Gastritis is a very common disease in children. The main presentation of children with gastritis is recurrent abdominal pain and dyspepsia or vomiting. Young children may have hematemesis or melena as presentation. Drug induced or food related gastritis presents usually with acute symptoms but Helicobacter pylori gastritis have mainly recurrent abdominal pain and dyspeptic symptoms. Other presentations include diarrhea, constipation, flatulence, bloating, fatigue, low energy level, weight loss, muscle loss, bad breath etc.

The main causes of gastritis are infections, inflammation and other disorders affect the gastric mucosa in pediatric patients. Helicobacter pylori infection is the most common cause of gastritis in children which is also responsible for the majority of duodenal ulcers.

Acute erosive gastritis is most commonly the result of metabolic stress or drug or corrosive injury.

Other major causes of gastritis include celiac disease, allergic disorders, and Crohn's disease .Medication as NSAIDs, uremia, ischemia, shock, radiation, sepsis, trauma, severe burns and surgery.

Endoscopic pictures in acute gastritis may be in the form of:

  • Multiple round-shaped severe erosions with a diameter of several millimeters.
  • Mucosal edema, hyperemia.
  • Peptic ulcer While in chronic gastritis is variable. Affects the antrum in the beginning and advances to the proximal in time .

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Study Type : Observational
Estimated Enrollment : 500 participants
Observational Model: Case-Control
Time Perspective: Retrospective
Official Title: Retrospective Study on Endoscopic Findings of Gastritis in Children Attending GIT Endoscopic Unit of Assiut University Children Hospital (AUCH) (15 Years)
Estimated Study Start Date : September 30, 2020
Estimated Primary Completion Date : October 30, 2020
Estimated Study Completion Date : April 30, 2021

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Endoscopy

Primary Outcome Measures :
  1. causes of gastritis in children as shown by upper endoscopy [ Time Frame: average 1 year ]
    • infections
    • inflammation
    • Helicobacter pylori
    • Acute erosive gastritis

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Ages Eligible for Study:   up to 18 Years   (Child, Adult)
Sexes Eligible for Study:   All
Sampling Method:   Non-Probability Sample
Study Population
All children diagnosed as gastritis by upper endoscopy and bio gastric biopsy

Inclusion Criteria:

  • All children diagnosed as gastritis by upper endoscopy and bio gastric biopsy

Exclusion Criteria:

  • • All children underwent upper endoscopy during the study period not diagnosed as gastritis

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04289519

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Contact: Naglaa Hassan, Professor 01111872237 naglaa.ibrahim@med.au.edu.eg
Contact: Amira Mohamed, Lecturer 01223958949 amira.shalabi@med.au.edu.eg

Sponsors and Collaborators
Assiut University
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Responsible Party: HM Reyad, principle investigator, Assiut University
ClinicalTrials.gov Identifier: NCT04289519    
Other Study ID Numbers: EFOGIC
First Posted: February 28, 2020    Key Record Dates
Last Update Posted: February 28, 2020
Last Verified: February 2020

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Additional relevant MeSH terms:
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Gastrointestinal Diseases
Digestive System Diseases
Stomach Diseases