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CT Scores Predict Mortality in 2019-nCoV Pneumonia

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT04284046
Recruitment Status : Completed
First Posted : February 25, 2020
Last Update Posted : February 25, 2020
Sponsor:
Information provided by (Responsible Party):
Ruilan Wang, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

Study Description
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Brief Summary:
While 2019-nCoV nucleic acid swab tests has high false positives rate, How to diagnose 2019-nCoV pneumonia and predict prognosis by CT is very important.In this retrospective single-center study, we consecutively included suspected 2019-nCoV pneumonia critical cases in the intensive care unit of Wuhan third hospital from January 31, 2020 to February 16, 2020. The cases were confirmed by real-time RT-PCR, and all patients were evaluated with CT, cutoff values were obtained according to the Yoden index, and were divided into high CT score group and low CT score group. Epidemiological, demographic, clinical, and laboratory data were collected.

Condition or disease Intervention/treatment
CT Scores Predict Mortality in 2019-nCoV Pneumonia Other: CT score

Study Design
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Study Type : Observational
Actual Enrollment : 39 participants
Observational Model: Cohort
Time Perspective: Retrospective
Official Title: CT Scores Predict Mortality in 2019-nCoV Pneumonia
Actual Study Start Date : January 31, 2020
Actual Primary Completion Date : February 18, 2020
Actual Study Completion Date : February 18, 2020

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Pneumonia

Groups and Cohorts
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Group/Cohort Intervention/treatment
High CT score Other: CT score
CT score = normal lung tissue (%) ×1 + GGO (%) ×2 + consolidation (%) ×3
Low CTscore Other: CT score
CT score = normal lung tissue (%) ×1 + GGO (%) ×2 + consolidation (%) ×3


Outcome Measures
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Primary Outcome Measures :
  1. 7-day mortality [ Time Frame: 7-day ]

Eligibility Criteria
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Information from the National Library of Medicine

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Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
all patients suspected of 2019 novel coronavirus infection.
Criteria

Inclusion Criteria:

  • all patients suspected of 2019 novel coronavirus infection.

Exclusion Criteria:

  • patients' data are not available.
Contacts and Locations
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Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04284046


Locations
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China, Hubei
Wuhan third hospital
Wuhan, Hubei, China
Sponsors and Collaborators
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
More Information
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Top of Page Study Description Study Design Groups and Cohorts Outcome Measures Eligibility Criteria Contacts and Locations More Information
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Responsible Party: Ruilan Wang, PhD, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
ClinicalTrials.gov Identifier: NCT04284046    
Other Study ID Numbers: CT2019-nCoV
First Posted: February 25, 2020    Key Record Dates
Last Update Posted: February 25, 2020
Last Verified: February 2020

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Additional relevant MeSH terms:
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Pneumonia
Respiratory Tract Infections
Infections
Lung Diseases
Respiratory Tract Diseases