Longitudinal Study of Cell Free DNA in Lung Transplant (LoSt)
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|ClinicalTrials.gov Identifier: NCT04234919|
Recruitment Status : Enrolling by invitation
First Posted : January 21, 2020
Last Update Posted : August 4, 2020
|Condition or disease|
|Lung Transplant Rejection|
|Study Type :||Observational|
|Estimated Enrollment :||75 participants|
|Official Title:||A Longitudinal Study of Donor-Derived Cell Free DNA in Lung Transplant|
|Actual Study Start Date :||March 19, 2020|
|Estimated Primary Completion Date :||February 1, 2022|
|Estimated Study Completion Date :||February 1, 2022|
|Consented adult lung transplant recipients|
- Relationship [ Time Frame: 12 Months ]Determine the relationship between donor derived cell free DNA and lung allograft function during the first year after lung transplant.
- Quantitative Assessments [ Time Frame: 12 Months ]Quantitative assessments of dd-cfDNA obtained at pre-specified timepoints post-transplant compared to clinical events (PGD scores, detection of allograft dysfunction, rejection, or infection).
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04234919
|United States, Colorado|
|University of Colorado, Denver|
|Aurora, Colorado, United States, 80045|
|Principal Investigator:||Alice L Gray, MD||University of Colorado, Denver|