Working…
ClinicalTrials.gov
ClinicalTrials.gov Menu

Effects of Neuromobilization on Median Nerve Elasticity

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT04218175
Recruitment Status : Completed
First Posted : January 6, 2020
Last Update Posted : July 30, 2020
Sponsor:
Information provided by (Responsible Party):
Yasemin Çırak, Istinye University

Brief Summary:

Purpose: The aim of this study was to investigate the effect of median nerve neuromobilization on median nerve elasticity using shear wave elastography.

Methods: The study included 36 healthy volunteers (72 upper extremities) aged 18-30 years. Inclusion criteria; no known systemic neuromuscular and metabolic diseases, no nerve impingement syndrome, and no upper extremity bone-tendon-muscle surgery in the last six months. Sociodemographic data of the participants were recorded. Wrist flexion and extension bilaterally with universal goniometer and finger grip strength bilaterally were measured with pinchmeter. Median Nerve Stress Test was performed. Median nerve elasticity was measured by Shear Wave Ultrasound Elastography. The extremity of the dominant side as a study group and the non-dominant side as a control group were measured bilaterally. Median nerve neuromobilization (stretching (n = 18) and shifting (n = 18)) was applied to the upper extremities of the dominant side. The application was carried out as 3 sets in one session. Evaluations were repeated after application.


Condition or disease Intervention/treatment Phase
Median Nerve Disease Other: neuromobilization exercises Not Applicable

Layout table for study information
Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 18 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Intervention Model Description: The researcher who performed shear wave elastography did not know which group the case was evaluated during the measurement.
Masking: Single (Outcomes Assessor)
Primary Purpose: Treatment
Official Title: Effects of Neuromobilization on Median Nerve Elasticity
Actual Study Start Date : November 10, 2019
Actual Primary Completion Date : December 15, 2019
Actual Study Completion Date : December 25, 2019

Arm Intervention/treatment
Experimental: neuromobilization stretching group
In the neuromobilization stretching group; The subjects were brought to shoulder depression and 90 degrees of abduction while the dominant side forearms were supination. In this position, median nerve stretching was performed by extending the participant's head to the opposite side while flexing the wrist and finger. After waiting for 30 seconds in this position, the wrist and head were moved to the neutral position and the participants relaxed.
Other: neuromobilization exercises
Median nerve neuromobilization (stretching and shifting) was performed. For median nerve stretching; The subjects were brought to shoulder depression and 90 degrees of abduction while the dominant side forearms were supination. In this position, median nerve stretching was performed by extending the participant's head to the opposite side while flexing the wrist and finger. After waiting for 30 seconds in this position, the wrist and head were moved to the neutral position and the participants relaxed. For median nerve shift; The subjects were brought to shoulder depression and 90 degrees of abduction while the dominant side forearms were supination. In this position, the participant flexed his wrist and fingers while lateral flexion of his head to the opposite side, and flexed his wrist and fingers while lateral flexion of the head to the same side.

Experimental: neuromobilization shifting group
In the neuromobilization shifting group, the subjects were brought to shoulder depression and 90 degrees of abduction while the dominant forearms were supination. In this position, the participant flexed his wrist and fingers while lateral flexion of his head to the opposite side, and flexed his wrist and fingers while lateral flexion of the head to the same side. Thus, the participants performed median nerve shift.
Other: neuromobilization exercises
Median nerve neuromobilization (stretching and shifting) was performed. For median nerve stretching; The subjects were brought to shoulder depression and 90 degrees of abduction while the dominant side forearms were supination. In this position, median nerve stretching was performed by extending the participant's head to the opposite side while flexing the wrist and finger. After waiting for 30 seconds in this position, the wrist and head were moved to the neutral position and the participants relaxed. For median nerve shift; The subjects were brought to shoulder depression and 90 degrees of abduction while the dominant side forearms were supination. In this position, the participant flexed his wrist and fingers while lateral flexion of his head to the opposite side, and flexed his wrist and fingers while lateral flexion of the head to the same side.

No Intervention: Control Group
The dominant sides of the individuals are experimental sides and the other nondominant sides of the participants are control sides. And no intervention was made. All measurements were done bilaterally before and after.



Primary Outcome Measures :
  1. Median Nerve Tension Test [ Time Frame: 4 weeks ]
    The test was performed in a position with shoulder depression and 90 degrees abduction and external rotation, elbow 90 degrees flexion, forearm full supination, and wrist and fingers fully extended. Maintaining this position, the elbow was passively extended and the tension of the median nerve was tested. The test was stopped at the point where the patient felt pain and tension, and the angle at the elbow was measured by a universal goniometer.

  2. Median nerve elasticity with Shear Wave Ultrasound Elastography [ Time Frame: 4 weeks ]
    The nerve elasticity was measured by measuring the velocity of shear waves in the median nerve by means of high frequency ultrasound waves.

  3. Bilaterally finger grip strength with pinchmeter [ Time Frame: 4 weeks ]
    finger grip strength was measured bilaterally by pinch meter.



Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Layout table for eligibility information
Ages Eligible for Study:   18 Years to 30 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • 18-30 years of age
  • Healthy individuals without any known systemic disease

Exclusion Criteria:

  • Those who have undergone an upper extremity bone-tendon-muscle operation in the last six months
  • People with a systemic disease such as rheumatoid arthritis, diabetes mellitus
  • Patients with any neuromuscular disease

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04218175


Locations
Layout table for location information
Turkey
İstinye University
Istanbul, Turkey, 34010
Sponsors and Collaborators
Istinye University
Layout table for additonal information
Responsible Party: Yasemin Çırak, Physiotherapist, PhD, Associate Professor, Istinye University
ClinicalTrials.gov Identifier: NCT04218175    
Other Study ID Numbers: 005
First Posted: January 6, 2020    Key Record Dates
Last Update Posted: July 30, 2020
Last Verified: July 2020

Layout table for additional information
Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Keywords provided by Yasemin Çırak, Istinye University:
neuromobilization
elasticity
shear wave elastography
Additional relevant MeSH terms:
Layout table for MeSH terms
Nervous System Diseases
Median Neuropathy
Mononeuropathies
Peripheral Nervous System Diseases
Neuromuscular Diseases