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Assessment of Two Point Discrimination

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ClinicalTrials.gov Identifier: NCT04207073
Recruitment Status : Completed
First Posted : December 20, 2019
Last Update Posted : November 17, 2021
Sponsor:
Information provided by (Responsible Party):
Gülay Aras, Medipol University

Brief Summary:
When the studies in the literature are examined, no study has been reached to examine whether median nerve mobilization causes changes in two-point discriminatory values in healthy individuals. This study aimed to investigate the effect of median nerve mobilization exercise on two-point discrimination in healthy adult male and female participants. Secondly, it was aimed to determine the role of variables such as gender, age, BMI (weight in kilograms, height in meters and weight and height will be combined to report BMI in kg/m^2), smoking, dominant extremity and physical activity level in 2-point discrimination.

Condition or disease Intervention/treatment Phase
Assessment, Self Device: Mobilization of median nerve Not Applicable

Detailed Description:

Two-point discrimination is one of the most important cortical senses that require strong tactile sensitivity and the ability to distinguish two points from one point on the skin. Neural mobilization has been reported to be effective in the nerve-related waist, leg, neck, arm, and plantar heel pain, but there is still insufficient evidence for other neuromusculoskeletal problems. It has been stated that factors such as application technique, type and patient characteristics of mobilization are effective in the treatment and more comprehensive studies should be done on this subject. This study aimed to investigate the effect of median nerve mobilization exercise on two-point discrimination in healthy adult male and female participants.

120 healthy female and male adult individuals (60 females, 60 males) will be included in the study. Individuals will be divided into two groups as female and male (n = 60), and a two-point discrimination test will be performed on the palmar face of both hands from the distal phalanx, forefinger, middle finger and palm. After the evaluation, the participants in both groups were randomly divided into two groups as the exercise group (n = 30) and control group (n = 30). Participants in the exercise group will perform 2 sets of 5 repetitive Median nerve mobilization exercises (total of 20 sessions) per day for 10 days. After the exercise program, the two-point discrimination measures will be repeated in all groups.

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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 120 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Intervention Model Description: Randomized Controlled Study
Masking: None (Open Label)
Primary Purpose: Health Services Research
Official Title: The Effect of Median Nerve Mobilization on Two Point Discrimination
Actual Study Start Date : December 23, 2019
Actual Primary Completion Date : April 24, 2021
Actual Study Completion Date : June 26, 2021

Arm Intervention/treatment
No Intervention: Control group
No intervention.
Experimental: Exercise group
Participants in the exercise group will perform 2 sets of 5 repetitive Median nerve mobilization exercises (total of 20 sessions) per day for 10 days.
Device: Mobilization of median nerve
Neural mobilization




Primary Outcome Measures :
  1. Two-point discrimination [ Time Frame: 2 weeks ]
    Two-point discrimination test will be performed on the palmar face of both hands from the distal phalanx, forefinger, middle finger and palm.



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Ages Eligible for Study:   20 Years to 25 Years   (Adult)
Sexes Eligible for Study:   All
Gender Based Eligibility:   Yes
Gender Eligibility Description:   60 females, and 60 males
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Healthy Volunteers
  • Adapt to median nerve mobilization exercise

Exclusion Criteria:

  • Upper extremity neuromuscular disease
  • The presence of neurological disease
  • Skin diseases (burn or scar tissue in upper extremity)
  • Diabetes mellitus

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04207073


Locations
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Turkey
Istanbul Medipol University
Istanbul, Turkey
Sponsors and Collaborators
Medipol University
Investigators
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Study Director: Candan Algun, Prof. Medipol University
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Responsible Party: Gülay Aras, PhD PT, Medipol University
ClinicalTrials.gov Identifier: NCT04207073    
Other Study ID Numbers: 10840098-604.01.01-E.63690
First Posted: December 20, 2019    Key Record Dates
Last Update Posted: November 17, 2021
Last Verified: November 2021
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Keywords provided by Gülay Aras, Medipol University:
two-point discrimination
neural mobilization
tactile sensation
median nerve