Assessment of Two Point Discrimination
![]() |
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. |
ClinicalTrials.gov Identifier: NCT04207073 |
Recruitment Status :
Completed
First Posted : December 20, 2019
Last Update Posted : November 17, 2021
|
- Study Details
- Tabular View
- No Results Posted
- Disclaimer
- How to Read a Study Record
Condition or disease | Intervention/treatment | Phase |
---|---|---|
Assessment, Self | Device: Mobilization of median nerve | Not Applicable |
Two-point discrimination is one of the most important cortical senses that require strong tactile sensitivity and the ability to distinguish two points from one point on the skin. Neural mobilization has been reported to be effective in the nerve-related waist, leg, neck, arm, and plantar heel pain, but there is still insufficient evidence for other neuromusculoskeletal problems. It has been stated that factors such as application technique, type and patient characteristics of mobilization are effective in the treatment and more comprehensive studies should be done on this subject. This study aimed to investigate the effect of median nerve mobilization exercise on two-point discrimination in healthy adult male and female participants.
120 healthy female and male adult individuals (60 females, 60 males) will be included in the study. Individuals will be divided into two groups as female and male (n = 60), and a two-point discrimination test will be performed on the palmar face of both hands from the distal phalanx, forefinger, middle finger and palm. After the evaluation, the participants in both groups were randomly divided into two groups as the exercise group (n = 30) and control group (n = 30). Participants in the exercise group will perform 2 sets of 5 repetitive Median nerve mobilization exercises (total of 20 sessions) per day for 10 days. After the exercise program, the two-point discrimination measures will be repeated in all groups.
Study Type : | Interventional (Clinical Trial) |
Actual Enrollment : | 120 participants |
Allocation: | Randomized |
Intervention Model: | Parallel Assignment |
Intervention Model Description: | Randomized Controlled Study |
Masking: | None (Open Label) |
Primary Purpose: | Health Services Research |
Official Title: | The Effect of Median Nerve Mobilization on Two Point Discrimination |
Actual Study Start Date : | December 23, 2019 |
Actual Primary Completion Date : | April 24, 2021 |
Actual Study Completion Date : | June 26, 2021 |
Arm | Intervention/treatment |
---|---|
No Intervention: Control group
No intervention.
|
|
Experimental: Exercise group
Participants in the exercise group will perform 2 sets of 5 repetitive Median nerve mobilization exercises (total of 20 sessions) per day for 10 days.
|
Device: Mobilization of median nerve
Neural mobilization |
- Two-point discrimination [ Time Frame: 2 weeks ]Two-point discrimination test will be performed on the palmar face of both hands from the distal phalanx, forefinger, middle finger and palm.

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
Ages Eligible for Study: | 20 Years to 25 Years (Adult) |
Sexes Eligible for Study: | All |
Gender Based Eligibility: | Yes |
Gender Eligibility Description: | 60 females, and 60 males |
Accepts Healthy Volunteers: | Yes |
Inclusion Criteria:
- Healthy Volunteers
- Adapt to median nerve mobilization exercise
Exclusion Criteria:
- Upper extremity neuromuscular disease
- The presence of neurological disease
- Skin diseases (burn or scar tissue in upper extremity)
- Diabetes mellitus

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04207073
Turkey | |
Istanbul Medipol University | |
Istanbul, Turkey |
Study Director: | Candan Algun, Prof. | Medipol University |
Responsible Party: | Gülay Aras, PhD PT, Medipol University |
ClinicalTrials.gov Identifier: | NCT04207073 |
Other Study ID Numbers: |
10840098-604.01.01-E.63690 |
First Posted: | December 20, 2019 Key Record Dates |
Last Update Posted: | November 17, 2021 |
Last Verified: | November 2021 |
Individual Participant Data (IPD) Sharing Statement: | |
Plan to Share IPD: | No |
Studies a U.S. FDA-regulated Drug Product: | No |
Studies a U.S. FDA-regulated Device Product: | No |
two-point discrimination neural mobilization tactile sensation median nerve |