Aspirin Effects on Emotional Reactions
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|ClinicalTrials.gov Identifier: NCT04146532|
Recruitment Status : Suspended (The study was suspended due to COVID-19 cessation of research activities in March of 2020)
First Posted : October 31, 2019
Last Update Posted : April 30, 2020
|Condition or disease||Intervention/treatment||Phase|
|Healthy Adults||Drug: Aspirin 500 MG Drug: Placebo||Early Phase 1|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||200 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||Double (Participant, Care Provider)|
|Primary Purpose:||Basic Science|
|Official Title:||Effects of Aspirin on Emotional Reactivity, Memory, and Risk-taking|
|Actual Study Start Date :||October 8, 2019|
|Estimated Primary Completion Date :||October 8, 2021|
|Estimated Study Completion Date :||October 8, 2021|
Placebo Comparator: Placebo
Single dose of a 500mg placebo tablet.
Single 500mg placebo capsule.
Active Comparator: Aspirin 500MG
Single dose of a 500 mg aspirin tablet.
Drug: Aspirin 500 MG
Single 500mg aspirin capsule.
Other Name: actelysalicylic acid
- Emotional Reactivity [ Time Frame: 1.5 hours ]Changes in self-reported evaluations of valence on a 1 to 7 scale and felt reactions to emotional images on a 1-7 scale.
- Memory [ Time Frame: 1.5 hours ]Changes in memory for emotional pictures. After rating the images, the participants will be shown them again as well as new pictures and asked to indicate whether they have seen the picture before or not.
- Risk-Taking [ Time Frame: 1.5 hours ]We will measure the adjusted average number of pumps on the Balloon Analogue Risk Task.
- Individual Differences [ Time Frame: 1.5 hours ]Self-reported political ideology will be examined as a moderator of the self-reported ratings of the images as well as memory for them.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04146532
|United States, Ohio|
|Columbus, Ohio, United States, 43210|