Working…
ClinicalTrials.gov
ClinicalTrials.gov Menu

Is Asthma in Subjects With Obstructive Sleep Apnoea (OSA) Due to Dysanapsis

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT04142905
Recruitment Status : Not yet recruiting
First Posted : October 29, 2019
Last Update Posted : October 8, 2020
Sponsor:
Information provided by (Responsible Party):
Julie Dawson, Norfolk and Norwich University Hospitals NHS Foundation Trust

Brief Summary:
Intention to review patient letters from sleep clinic to see if their lung function fit in with Dysynapsis in wheezing patients or if it is true asthma

Condition or disease
Asthma Obstructive Sleep Apnoea (OSA) Dysanapis

Show Show detailed description

Layout table for study information
Study Type : Observational
Estimated Enrollment : 200 participants
Observational Model: Other
Time Perspective: Retrospective
Official Title: Is Asthma in Subjects With Obstructive Sleep Apnoea (OSA) Due to Dysanapsis
Estimated Study Start Date : December 1, 2020
Estimated Primary Completion Date : October 1, 2025
Estimated Study Completion Date : October 1, 2025

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Asthma Sleep Apnea

Group/Cohort
Patients With Asthma
Subjects with sleep disordered breathing with asthma
Patients Without Asthma
Subjects with sleep disordered breathing without asthma



Primary Outcome Measures :
  1. Defined dysynapsis in patients with asthma and obstructive sleep apnoea (OSA) [ Time Frame: 6 years ]
    The investigator will refer to the Sleep Disordered Breathing Clinic records to investigate the prevalence of dysanapsis in patients with Sleep disordered breathing, in patients with asthma compared to those without asthma.


Secondary Outcome Measures :
  1. Apnea-Hypopnea Index (AHI) [ Time Frame: 6 years ]
    The investigator will refer to the Sleep Disordered Breathing Clinic records to compare measures of Apnea-Hypopnea Index (AHI) in patients with and without asthma.

  2. Eosinophil count [ Time Frame: 6 years ]
    The investigator will refer to the Sleep Disordered Breathing Clinic records to compare Eosinophil count in patients with and without asthma.



Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Layout table for eligibility information
Ages Eligible for Study:   18 Years to 99 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
Adult patients attending the Obstructive Sleep Apnea Clinic at Norfolk & Norwich University Hospital NHS Foundation Trust
Criteria

Inclusion Criteria:

  • Any subject in Obstructive Sleep Apnea clinic.

Exclusion Criteria:

  • Only exclusion criteria is if they have no recorded lung function in their notes

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04142905


Contacts
Layout table for location contacts
Contact: Sadiyah Hand, Dr 01603286286 sadiyah.hand@nnuh.nhs.uk

Sponsors and Collaborators
Julie Dawson
Publications:

Layout table for additonal information
Responsible Party: Julie Dawson, Research Services Manager, Norfolk and Norwich University Hospitals NHS Foundation Trust
ClinicalTrials.gov Identifier: NCT04142905    
Other Study ID Numbers: 269072
First Posted: October 29, 2019    Key Record Dates
Last Update Posted: October 8, 2020
Last Verified: October 2020

Layout table for additional information
Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Additional relevant MeSH terms:
Layout table for MeSH terms
Asthma
Apnea
Sleep Apnea Syndromes
Sleep Apnea, Obstructive
Bronchial Diseases
Respiratory Tract Diseases
Lung Diseases, Obstructive
Lung Diseases
Respiratory Hypersensitivity
Hypersensitivity, Immediate
Hypersensitivity
Immune System Diseases
Respiration Disorders
Signs and Symptoms, Respiratory
Sleep Disorders, Intrinsic
Dyssomnias
Sleep Wake Disorders
Nervous System Diseases