Expression of Trefoil Factors and Adrenomedullin in Subjects With Chronic Periodontitis and Coronary Heart Disease
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|ClinicalTrials.gov Identifier: NCT04127474|
Recruitment Status : Recruiting
First Posted : October 15, 2019
Last Update Posted : October 15, 2019
|Condition or disease|
|Coronary Heart Disease Periodontal Diseases|
A total of 75 subjects will be recruited for the study based on the power of the study.
The selected subjects will be divided into 3 groups based on inclusion and exclusion criteria.
GROUP I:25Generalized chronic periodontitis subjects without coronary heart disease.
GROUP II: 25Generalized chronic periodontitis subjects diagnosed with coronary heart disease.
GROUP III: 25Periodontally healthy subjects diagnosed with coronary heart disease.
Demographic variables, periodontal parameters and biochemical parameters will be measured in all three groups
|Study Type :||Observational|
|Estimated Enrollment :||75 participants|
|Official Title:||Expression of Trefoil Factors 2 and 3 and Adrenomedullin in Unstimulated Saliva Samples of Chronic Periodontitis Subjects With and Without Coronary Heart Disease|
|Actual Study Start Date :||October 14, 2019|
|Estimated Primary Completion Date :||December 20, 2019|
|Estimated Study Completion Date :||November 20, 2021|
25 Generalized chronic periodontitis subjects without coronary heart disease.
25 Generalized chronic periodontitis subjects diagnosed with coronary heart disease.
25 Periodontally healthy subjects diagnosed with coronary heart disease.
- Trefoil factors 2 and 3 and Adrenomedullin expression in Chronic periodontitis patients with and without coronary heart disease [ Time Frame: 12 months ]Expression of Trefoil factors 2 and 3 and Adrenomedullin using Enzyme Linked Immunosorbent Assay
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04127474
|Contact: Jaideep Mahendra, MDS, PhDfirstname.lastname@example.org|
|Contact: Sruthi Srinivasan, BDSemail@example.com|
|Meenakshi Ammal Dental College||Recruiting|
|Chennai, Tamil Nadu, India, 600095|
|Contact: Jaideep Mahendra, MDS, PhD 9444963973 firstname.lastname@example.org|
|Contact: Sruthi Srinivasan, BDS 9962152960 email@example.com|
|Sub-Investigator: Sruthi Srinivasan, BDS|
|Principal Investigator: Jaideep Mahendra, MDS, PhD|
|Study Director:||Jaideep Mahendra, MDS, PhD||Meenakshi Ammal Dental College|