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Prevalence of Sarcopenia in Geriatric Patients

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ClinicalTrials.gov Identifier: NCT04124575
Recruitment Status : Recruiting
First Posted : October 11, 2019
Last Update Posted : October 17, 2019
Sponsor:
Information provided by (Responsible Party):
University Department of Geriatric Medicine FELIX PLATTER

Brief Summary:
To assess the prevalence of sarcopenia among inpatients on acute geriatrics and geriatric rehabilitation wards of a Swiss university department of geriatric medicine using the most recent diagnosis definitions from european guidelines.

Condition or disease
Sarcopenia

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Study Type : Observational
Estimated Enrollment : 350 participants
Observational Model: Other
Time Perspective: Cross-Sectional
Official Title: Prevalence of Sarcopenia in Patients Admitted to a Swiss University Department of Geriatric Medicine
Actual Study Start Date : September 10, 2019
Estimated Primary Completion Date : April 2020
Estimated Study Completion Date : July 2020



Primary Outcome Measures :
  1. Presence of Sarcopenia (yes/no) [ Time Frame: Baseline ]
    Using EWGSOP2 cut-off points

  2. Muscle quantity, measured by Body Impedance Analysis (kg) [ Time Frame: Baseline ]
  3. Hand Grip Strength (kPa) [ Time Frame: Baseline ]
  4. Gait Speed (m/s) [ Time Frame: Baseline ]
  5. Timed up and go Test (s) [ Time Frame: Baseline ]

Secondary Outcome Measures :
  1. Mini Mental Status (Score range from 0 to 30 Points; higher scores reflect better cognitive status) [ Time Frame: Baseline ]
  2. Nutritional risk Screening (Score range from 0 to 7 Points; higher scores reflect higher risk of malnutrition) [ Time Frame: Baseline ]
  3. Geriatric Depression Scale short version (Score range from 0 to 6 Points; higher scores reflect higher risk of depression) [ Time Frame: Baseline ]
  4. Functional Independence Measure at Admission (Score range from 18 to 126 Points; higher scores reflect better functionality) [ Time Frame: Baseline ]
  5. Calf and Mid-upper arm Circumference (cm) [ Time Frame: Baseline ]
  6. Body Mass Index (kg/m^2) [ Time Frame: Baseline ]
    Weight and height will be combined to report Body Mass Index in kg/m^2



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Ages Eligible for Study:   65 Years and older   (Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
The study population will be selected by the University Department of Geriatric Medicine FELIX PLATTER
Criteria

Inclusion Criteria:

- All patients >65 years old admitted to acute geriatrics and geriatric rehabilitation at the study site

Exclusion Criteria:

  • Lack of informed written consent
  • Implanted defibrillation device
  • Acute Sepsis, severe volume overload or dehydration
  • Life expectancy of < 3 months according to treating physician
  • Unremovable bandages
  • Patients in isolation rooms on the ward
  • Measurement is not possible due to organizational reasons
  • Inability to follow the procedures, e.g. due to language problems, psychological disorders

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04124575


Contacts
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Contact: Dominic K. Bertschi, Dr. +41 61 326 41 41 dominic.bertschi@felixplatter.ch
Contact: Caroline Kiss, Dr. +41 61 326 41 41 caroline.kiss@felixplatter.ch

Locations
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Switzerland
University Department of Geriatric Medicine FELIX PLATTER Recruiting
Basel, Switzerland
Contact: Dominic K. Bertschi, Dr.    +41 61 326 41 41    dominic.bertschi@felixplatter.ch   
Contact: Caroline Kiss, Dr.    +41 61 326 41 41    caroline.kiss@felixplatter.ch   
Sponsors and Collaborators
University Department of Geriatric Medicine FELIX PLATTER
Investigators
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Principal Investigator: Dominic K. Bertschi, Dr. University Department of Geriatric Medicine FELIX PLATTER
Study Chair: Caroline Kiss, Dr. University Department of Geriatric Medicine FELIX PLATTER
Study Director: Reto W. Kressig, Prof. Dr. University Department of Geriatric Medicine FELIX PLATTER

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Responsible Party: University Department of Geriatric Medicine FELIX PLATTER
ClinicalTrials.gov Identifier: NCT04124575     History of Changes
Other Study ID Numbers: BASEC 2019-01461
First Posted: October 11, 2019    Key Record Dates
Last Update Posted: October 17, 2019
Last Verified: October 2019
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Keywords provided by University Department of Geriatric Medicine FELIX PLATTER:
Prevalence
Sarcopenia
Geriatric
Additional relevant MeSH terms:
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Sarcopenia
Muscular Atrophy
Neuromuscular Manifestations
Neurologic Manifestations
Nervous System Diseases
Atrophy
Pathological Conditions, Anatomical
Signs and Symptoms