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Trial record 49 of 176 for:    Recruiting, Not yet recruiting, Available Studies | Chest pain

Retrospective Clinical Study on Adjuvant Treatment of Coronary Heart Disease Angina Pectoris With Chinese Patent Medicine (RCSCD-TCM)

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ClinicalTrials.gov Identifier: NCT04026724
Recruitment Status : Not yet recruiting
First Posted : July 19, 2019
Last Update Posted : July 19, 2019
Sponsor:
Information provided by (Responsible Party):
Chunquan Yu, Tianjin University of Traditional Chinese Medicine

Brief Summary:
A retrospective cohort study was performed in patients with angina pectoris who were treated with oral Chinese patent medicine and Western medicine.The hospital's medical record management system was used to collect symptoms of angina pectoris, dose and frequency of nitroglycerin use, clinical biochemical test and imaging examination.To explore the clinical efficacy of Chinese patent medicine in the treatment of coronary heart disease with angina pectoris, and provide reliable data support for its clinical application.

Condition or disease Intervention/treatment
Atherosclerotic Heart Disease With Angina Nos Drug: Chinese patent medicine

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Study Type : Observational
Estimated Enrollment : 12400 participants
Observational Model: Cohort
Time Perspective: Retrospective
Official Title: Retrospective Cohort Study on Adjuvant Treatment of Coronary Heart Disease Angina Pectoris With Chinese Patent Medicine
Estimated Study Start Date : September 1, 2019
Estimated Primary Completion Date : March 1, 2020
Estimated Study Completion Date : September 1, 2020

Resource links provided by the National Library of Medicine


Group/Cohort Intervention/treatment
Exposed group
Chinese patent medicine combined with western medicine routine treatment
Drug: Chinese patent medicine
Shexiang Baoxin Pill, Tongxinluo Capsule, Tongmai Yangxin Pill, Xuefu Zhuyu Capsule, Qishen Yiqi Dropping Pill.

Non-exposed group
Western medicine routine treatment



Primary Outcome Measures :
  1. Symptoms of angina [ Time Frame: one year ]
  2. Dosage and frequency of use of nitroglycerin [ Time Frame: one year ]
  3. Clinical biochemical indicators test [ Time Frame: one year ]
  4. Film degree exam [ Time Frame: one year ]


Information from the National Library of Medicine

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Ages Eligible for Study:   35 Years to 75 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Sampling Method:   Non-Probability Sample
Study Population
The collaboration network of coronary heart disease research medical units formed by the research group, including the First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, the Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin Nankai Hospital, Tianjin Chest Hospital, Tianjin Medical University General Hospital, a total of 5 hospitals.
Criteria

Inclusion Criteria:

  1. Age 35-75 years old, gender is not limited;
  2. Admission time is September 1, 2014 - September 1, 1919;
  3. Patients with coronary heart disease and angina pectoris in the Department of Cardiology or Outpatient Department, the diagnosis of angina pectoris meets the diagnostic criteria of Western medicine and the standard of TCM syndrome differentiation;
  4. Patients who met the criteria for drug treatment, the exposed group was treated with traditional Chinese medicine combined with Western medicine, and the non-exposed group was treated with Western medicine alone.

Exclusion Criteria:

  1. Combined with other heart diseases, neurosis, menopausal syndrome, hyperthyroidism, cervical or vertebral artery type cervical spondylosis, gastro-oesophageal reflux disease or esophageal hiatus hernia may cause chest pain;
  2. patients with acute myocardial infarction, heart failure, myocarditis, cardiomyopathy, severe heart valve disease, liver failure or renal failure, malignant tumors and severe metabolic diseases, as well as patients with severe symptoms and uncontrollable angina;
  3. Pregnant women, lactating women or women of childbearing age who have birth requirements;
  4. Mental patients, or cognitive dysfunction;
  5. The investigator believes that there are other situations that are not suitable for the trial.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04026724


Locations
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China, Tianjin
Tianjin University of Traditional Chinese Medicine Recruiting
Tianjin, Tianjin, China, 300193
Contact: Chunquan Yu, Dr.    8622-59596309    ycq-4@163.com   
Sponsors and Collaborators
Tianjin University of Traditional Chinese Medicine

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Responsible Party: Chunquan Yu, Director, Tianjin University of Traditional Chinese Medicine
ClinicalTrials.gov Identifier: NCT04026724     History of Changes
Other Study ID Numbers: RCSCD-TCM
First Posted: July 19, 2019    Key Record Dates
Last Update Posted: July 19, 2019
Last Verified: July 2019
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: Yes

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Additional relevant MeSH terms:
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Chest Pain
Pain
Heart Diseases
Angina Pectoris
Coronary Disease
Coronary Artery Disease
Myocardial Ischemia
Cardiovascular Diseases
Vascular Diseases
Neurologic Manifestations
Signs and Symptoms
Arteriosclerosis
Arterial Occlusive Diseases