Research of Circulating Tumor Cells Released During Endometrial Cancer Surgery. (E-CTC)
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT04021459|
Recruitment Status : Not yet recruiting
First Posted : July 16, 2019
Last Update Posted : July 16, 2019
|Condition or disease||Intervention/treatment||Phase|
|Endometrial Cancer||Procedure: blood samples||Not Applicable|
The goal of this single-center clinical trial is to determine the best blood punction site to observe the spreading of CTC during surgery in endometrial cancer. CTCs are very rare events on blood and their detection require extremely sensitive technologies. This pilot study will investigate CTC spread during surgery on 10 patients with endometrial cancer.
The main objective is to compare venipuncture site for detection of CTCs in endometrial cancer during surgery. Blood samples are collected on a simple sampling (arm) compared to sampling as close as possible to the tumor (ovarian vein).
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||10 participants|
|Intervention Model:||Single Group Assignment|
|Intervention Model Description:||women with endometrial cancer|
|Masking:||None (Open Label)|
|Official Title:||Preliminary Descriptive Exploratory Pilot Study Research of Circulating Tumor Cells Released During Endometrial Cancer Surgery|
|Estimated Study Start Date :||July 2019|
|Estimated Primary Completion Date :||July 2020|
|Estimated Study Completion Date :||July 2021|
|women with endometrial cancer||
Procedure: blood samples
3 samples: One before surgery on the arm vein (peripheral)
Two during the surgery, on two different venipuncture site :
- Qualitative assessment [ Time Frame: During surgery (at the ligature of the ovarian ligament) ]Presence or not of at least one CTC during endometrial cancer surgery detected on two venipuncture site (peripheral and ovarian vein).
- Quantitative assessment [ Time Frame: Before surgery and during surgery ]Number of CTC detected from each sampling
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04021459
|Contact: Gauthier RATHAT, PHDfirstname.lastname@example.org|
|Contact: Sarah FRANCINI, email@example.com|
|Montpellier University Hospital||Active, not recruiting|
|Montpellier, France, 34295|
|Principal Investigator:||Gauthier RATHAT, PHD||University of Montpellier|