The Relation Between Common Carotid Artery Diameter and Central Venous Pressure for Assessment of Intravascular Fluid Status After Major Surgeries: An Observational Study
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|ClinicalTrials.gov Identifier: NCT04018443|
Recruitment Status : Recruiting
First Posted : July 12, 2019
Last Update Posted : July 12, 2019
Recently, bedside ultrasound has become an important tool for the simple and non-invasive hemodynamic assessment of critically ill patients. This applies not only to echocardiography but also to ultrasound of large extra-thoracic veins. The sonography can provide real time assessment of the vascular system and hemodynamic status at the bedside.
To our knowledge, there is one report about the association between sonographically assessed carotid artery diameter and intravascular volume, which raised recommendation for further studies including the interplay between carotid geometry and intravascular fluid status.
Aim of the study:
The aim of this work is to evaluate the accuracy of noninvasive techniques for assessment of intravascular volume status by Sonographic assessment of both the common carotid artery diameter (CCA) and the central venous pressure (CVP) in response to a bolus of crystalloid solution infusion and to find the correlation between CCA diameter and CVP as the primary outcome in adults patients after major surgeries who needs close assessment and maintenance of the intravascular volume status.
|Condition or disease||Intervention/treatment|
|Fluid Resuscitation Monitoring Non-invasively||Diagnostic Test: common carotid artery diameter measurement|
|Study Type :||Observational [Patient Registry]|
|Estimated Enrollment :||60 participants|
|Target Follow-Up Duration:||6 Months|
|Official Title:||The Relation Between Common Carotid Artery Diameter and Central Venous Pressure for Assessment of Intravascular Fluid Status After Major Surgeries: An Observational Study|
|Actual Study Start Date :||April 7, 2019|
|Estimated Primary Completion Date :||October 7, 2019|
|Estimated Study Completion Date :||October 7, 2019|
patients admitted ti surgical ICU after major surgery
patient admitted to surgical ICU after major surgery for post-operative close monitoring, assessment and resuscitation of the intravascular volume status
Diagnostic Test: common carotid artery diameter measurement
measurement of common carotid artery diameter will be carried out two times: the initial measurement (pre-infusion) which is followed by infusion of crystalloid solution (Ringer lactate) 30 ml/min till reaching a total infusion volume of 7 ml/kg body weight then another ultrasound measurement will be taken (prost-infusion). Between these sequential measurements, the patient position will not be changed. The percentage increase in CCA diameter will be calculated using the formula: [(dia-mpost/dia-mpre) × 100] − 100 .
- Common Carotid Artery diameter at expiration (millimetre) [ Time Frame: 30 minutes before fluid bolus infusion ]common carotid artery internal diameter changes songraphically measured to assess intravenous resuscitation
- Common Carotid Artery diameter at expiration (millimetre) [ Time Frame: 5 minutesafter fluid bolus infusion ]common carotid artery internal diameter changes songraphically measured to assess intravenous resuscitation
- Central venous pressure (centimetre water) [ Time Frame: 5 minutes after fluid bolus infusion ]Central venous pressure changes measured to assess intravenous resuscitation
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04018443
|Contact: Samaa A. Kasem, MDemail@example.com|
|Banī Suwayf, Egypt, 62511|
|Contact: Tarek Al Menesy, MD +201141434355 firstname.lastname@example.org|
|Sub-Investigator: Ahmed A. BAdawy, MD|
|Sub-Investigator: Ashraf A. Mawgood, MD|
|Sub-Investigator: Yasmine A. Badawy, Medical Student|