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Effect of Cholesterol Level on Postoperative Acute Kidney Injury of Non-cardiac Surgeries

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ClinicalTrials.gov Identifier: NCT03954353
Recruitment Status : Recruiting
First Posted : May 17, 2019
Last Update Posted : May 24, 2019
Sponsor:
Information provided by (Responsible Party):
Yan Zhou, MD, Peking University First Hospital

Brief Summary:
Preoperative serum cholesterol level may influence occurrence of postoperative acute kidney injury of cardiac surgeries. However, the effect of Preoperative serum cholesterol level for non cardiac surgery remains unknown. This study aimed to explore the effect in non-cardiac surgical population.

Condition or disease
Acute Kidney Injury

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Study Type : Observational
Estimated Enrollment : 70000 participants
Observational Model: Other
Time Perspective: Retrospective
Official Title: Effect of Cholesterol Level on Postoperative Acute Kidney Injury of Non-cardiac Surgeries
Actual Study Start Date : May 17, 2019
Estimated Primary Completion Date : June 5, 2019
Estimated Study Completion Date : June 6, 2019

Resource links provided by the National Library of Medicine





Primary Outcome Measures :
  1. post-operative acute kidney injury within 30 days in the hospital [ Time Frame: 30 days postoperatively in hospital ]
    It was defined by patient's postoperative serum creatine increase no less than 26.5 μmol/l within 48 hours, or 1.5 times from baseline within the 7 days after surgery or initializing blood dialysis.



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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
adults (age ≥ 18 years old) who underwent elective non-cardiac surgery from January 1, 2012, to December 31, 2017.
Criteria

Inclusion Criteria:

adults elective non-cardiac surgery

Exclusion Criteria:

cardiac surgeries kidney surgeries obstetric surgeries local infiltration anesthesia perioperative data missing


Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03954353


Contacts
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Contact: Yan Zhou, MD, PhD 13641202040 anesth.zhouyan9@gmail.com

Locations
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China, Beijing
First hospital Peking University Recruiting
Beijing, Beijing, China, 100034
Contact: Yan Zhou, doctor    13641202040    anesth.zhouyan9@gmail.com   
Sponsors and Collaborators
Peking University First Hospital

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Responsible Party: Yan Zhou, MD, Principal Investigator, Peking University First Hospital
ClinicalTrials.gov Identifier: NCT03954353     History of Changes
Other Study ID Numbers: ECAKI
First Posted: May 17, 2019    Key Record Dates
Last Update Posted: May 24, 2019
Last Verified: May 2019
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: Undecided

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No

Additional relevant MeSH terms:
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Wounds and Injuries
Acute Kidney Injury
Renal Insufficiency
Kidney Diseases
Urologic Diseases