Brain Oxygenation During Prehospital Anesthesia (BOPRA-P)
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ClinicalTrials.gov Identifier: NCT03948711
Recruitment Status :
First Posted : May 14, 2019
Last Update Posted : February 16, 2021
Helsinki University Central Hospital
Oulu University Hospital
Information provided by (Responsible Party):
Jouni Nurmi, MD, Helsinki University Central Hospital
The study will evaluate the feasibility of Nonin SenSmart H500 device to measuring brain oxygenation during prehospital anesthesia of adult patient. The study also estimates the incidence of cerebral hypoxic events of anesthetized patients during prehospital care. The study does not affect the treatment of the patient. The study is pilot study and will be followed with a main study to assess the association between cerebral oxygenation during prehospital care and outcome of the patient.
Condition or disease
Device: Near-infrared spectroscopy (NIRS) monitoring of cerebral oxygenation
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Layout table for eligibility information
Ages Eligible for Study:
18 Years and older (Adult, Older Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Critically ill or trauma patients undergoing prehospital anesthesia and endotracheal intubation for any reason by helicopter emergency medical team providing critical care.
sedation or anesthesia provided to facilitate endotracheal intubation, performed by HEMS team regardless of the reason
Cardiac arrest at the time of intubation
Physical barrier for NIRS measuring (e.g. forehead laceration)
HEMS physician does not escort patient to the hospital (and patient is not dead on the scene after inclusion)
Workload too high to ensure standard level of clinical care during the study
Known special vulnerability including known mental disability (permanent, not related to acute condition), patients in nursing homes, prisoners and forensic psychiatric patients.