Penicillin Allergy Testing and Resensitization Rate (Penicillin)
|ClinicalTrials.gov Identifier: NCT03942731|
Recruitment Status : Completed
First Posted : May 8, 2019
Last Update Posted : July 31, 2019
|Condition or disease||Intervention/treatment|
|Penicillin Allergy||Other: Behavioral allergy testing protocol|
|Study Type :||Observational|
|Actual Enrollment :||83 participants|
|Official Title:||Resensitization Rate After Drug Provocation Test and Challenge in Eighty-three Adult Outpatients With a Distant Penicillin Allergy.|
|Actual Study Start Date :||February 1, 2019|
|Actual Primary Completion Date :||March 15, 2019|
|Actual Study Completion Date :||March 15, 2019|
83 adult outpatients at CHR Metz-Thionville with penicillin allergy label
Other: Behavioral allergy testing protocol
skin tests followed by drug provocation test and skin retesting between 6 weeks and 6 months
- efficacy of repeated skin testing [ Time Frame: week 4 ]verified efficacy of repeated skin testing 4 weeks or more after drug provocation test and challenge in distant penicillin allergic patients. The reagents used for skin testing were as follow: Penicillin G, Clamoxyl, Augmentin,Tienam, Histamine and Normal saline (negative control). A skin test producing a papule with a diameter greater then 3 mm is considered as positive.
- efficacy of allergy testing [ Time Frame: Week 4 ]efficacy of allergy testing in identifying penicillin hypersensitivity reactions. Patients were called to perform, once again skin testing because skin tests sooner could result in false negatives due to the temporary desensitized state.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03942731
|CHR Metz Thionville|
|Thionville, Moselle, France, 57100|
|Principal Investigator:||Sebastien Lefevre, MD||CHR Metz Thionville|