New Approaches for Empowering Studies of Asthma in Populations of African Descent
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT03937804|
Recruitment Status : Not yet recruiting
First Posted : May 6, 2019
Last Update Posted : June 25, 2019
Some groups of people have a high prevalence of asthma and allergic disease. Also, asthma and allergic disease are often found in several members of the same family. Researchers want to learn more about what factors might cause asthma, both genetic and environmental.
To build a collection of information to try to find genes that cause conditions and disorders such as asthma and allergic disease.
People ages 18 99 of self-identified African, African American, or African Caribbean descent who either have no history of asthma or wheeze or have a physician s diagnosis of asthma
Participants will be screened with an interview by phone or in person.
Participants will fill out a questionnaire about their general health and exposure to allergens and smoke.
Participants will have a physical exam.
Participants will have blood tests.
Participants will provide a skin cell sample. Up to two samples will be taken from the inside of the nose. A brush will be used to take the samples.
Participants will have a breathing test. They will be asked to blow forcefully 3 or more times into a lung function machine.
Participants may have their blood and skin samples sent to a lab. DNA will be extracted from the samples and tested.
Participants blood and skin samples will be stored. Samples may be used in future research studies.
|Condition or disease|
|Study Type :||Observational|
|Estimated Enrollment :||100 participants|
|Official Title:||New Approaches for Empowering Studies of Asthma in Populations of African Decent|
|Estimated Study Start Date :||June 28, 2019|
|Estimated Primary Completion Date :||July 31, 2020|
|Estimated Study Completion Date :||July 31, 2020|
persons with asthma
persons without asthma
- Expand and integrate multiomic resources for asthma research in African Diaspora populations and identify novel genetic determinants for risk of asthma in CAAPA cohorts [ Time Frame: single assessment ]Expand and integrate multiomic resources for asthma research in African Diaspora populations and identify novel genetic determinants for risk of asthma in CAAPA cohorts
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03937804
|Contact: Shirley Freeman||(301) email@example.com|
|United States, Maryland|
|National Institutes of Health Clinical Center||Not yet recruiting|
|Bethesda, Maryland, United States, 20892|
|Contact: For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR) 800-411-1222 ext TTY8664111010 firstname.lastname@example.org|
|Principal Investigator:||Charles N Rotimi, M.D.||National Human Genome Research Institute (NHGRI)|