Reliability and Validity of the Turkish Version of the Multiple Sclerosis Knowledge Questionnaire

• ClinicalTrials.gov Identifier: NCT03927092
• Recruitment Status: Completed
• First Posted: April 25, 2019
• Last Update Posted: April 29, 2019
• Sponsor: Ege University
• Information provided by (Responsible Party): Ece Cinar, Ege University

Study Description

Brief Summary:

Multiple Sclerosis Knowledge Questionnaire (MSKQ) is a 25-item self administered questionnaire assessing a patient's level of knowledge regarding multiple sclerosis (MS). Turkish translation of the questionnaire was prepared and participants in the annual patient education seminar in the investigators' university hospital were asked to answer these questions before and after the seminar.Their results were analysed to assess their level of knowledge about their disease.

Condition or disease	Intervention/treatment
Multiple Sclerosis	Other: Multiple Sclerosis Knowledge Questionnaire

Detailed Description:

Multiple sclerosis knowledge questionnaire was developed in Italy (1) and was reported to be useful in measuring patients' level of knowledge about their disease. The English version of the questionnaire was translated into Turkish by three physicians than back translated into English by two separate linguists. Initially 5 MS patients were asked to answer this first version of the questionnaire and report any difficulties in understanding the items. Their feedback was used to give the questionnaire its final shape. For the validation stage, patients that were diagnosed as having MS and who attended the annual MS patient education seminar were enrolled into the study. They answered the questions twice, before and after the seminar. Their answers were analysed to measure their level of knowledge about their disease.

Study Design

• Study Type: Observational
• Actual Enrollment: 58 participants
• Observational Model: Case-Only
• Time Perspective: Cross-Sectional
• Official Title: Reliability and Validity of the Turkish Version of the Multiple Sclerosis Knowledge Questionnaire
• Actual Study Start Date: May 2016
• Actual Primary Completion Date: May 2016
• Actual Study Completion Date: May 2016

Groups and Cohorts

Group/Cohort	Intervention/treatment
Multiple Sclerosis patients; Patients that attended an annual patient education seminar at the investigators' university hospital were asked to fill out the Turkish version of the Multiple Sclerosis Knowledge Questionnaire	Other: Multiple Sclerosis Knowledge Questionnaire; A 25-item self-administered questionnaire

Outcome Measures

Primary Outcome Measures :

1. reliability of the questionnaire [ Time Frame: 1 day ]
   Internal consistency was evaluated by the coefficient alpha (α) or Cronbach's coefficient, and if the Cronbach's coefficient value was greater than 0.7, it was considered as an acceptable internal consistency

Secondary Outcome Measures :

1. Number of correct answers [ Time Frame: 1 day ]
   To assess the distribution of correct and false answers and the levels of significance, Chi-square test was used. To compare the two questionnaires answered by the same patient before and after the seminar Wilcoxon signed-rank test was used.

Eligibility Criteria

• Ages Eligible for Study: 18 Years and older (Adult, Older Adult)
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: No
• Sampling Method: Non-Probability Sample

Study Population

Patients diagnosed as having multiple sclerosis.

Criteria

Inclusion Criteria:

• Diagnosed as having Multiple Sclerosis
• Attends the annual patient education seminar at the investigators' university hospital
• Older than 18 years of age
• Can read and write

Exclusion Criteria:

• Does not accept to answer the questionnaire
• Unable to answer the questions due to a cognitive impairment

Contacts and Locations

Sponsors and Collaborators

Ege University

Investigators

• Principal Investigator: Ece Cinar, M.D.; Ege University School of Medicine
• Study Director: Yesim Akkoc, M.D.; Ege University School of Medicine
• Principal Investigator: Funda Calis, M.D.; Ege University School of Medicine
• Principal Investigator: Musa Baklaci, M.D.; Ege University School of Medicine
• Principal Investigator: Ozgul Ekmekci, M.D.; Ege University School of Medicine
• Principal Investigator: Ayse N Yuceyar, M.D.; Ege University School of Medicine

More Information

Publications:

Giordano A, Uccelli MM, Pucci E, Martinelli V, Borreani C, Lugaresi A, Trojano M, Granella F, Confalonieri P, Radice D, Solari A; SIMS-Trial group. The Multiple Sclerosis Knowledge Questionnaire: a self-administered instrument for recently diagnosed patients. Mult Scler. 2010 Jan;16(1):100-11. doi: 10.1177/1352458509352865. Epub 2009 Dec 7.

• Responsible Party: Ece Cinar, Principal investigator, Ege University
• ClinicalTrials.gov Identifier: NCT03927092
• Other Study ID Numbers: 16-4.1/19
• First Posted: April 25, 2019
• Last Update Posted: April 29, 2019
• Last Verified: April 2019

Individual Participant Data (IPD) Sharing Statement:

• Plan to Share IPD: No

• Studies a U.S. FDA-regulated Drug Product: No
• Studies a U.S. FDA-regulated Device Product: No

Keywords provided by Ece Cinar, Ege University:

multiple sclerosis; surveys and questionnaires; diagnostic self evaluation

Additional relevant MeSH terms:

Multiple Sclerosis; Sclerosis; Pathologic Processes; Demyelinating Autoimmune Diseases, CNS; Autoimmune Diseases of the Nervous System; Nervous System Diseases; Demyelinating Diseases; Autoimmune Diseases; Immune System Diseases