Exploration and Verification of DNA Methylolation in Early Screening of Esophageal Cancer
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|ClinicalTrials.gov Identifier: NCT03922230|
Recruitment Status : Recruiting
First Posted : April 19, 2019
Last Update Posted : April 19, 2019
|Condition or disease|
|Esophageal Squamous Cell Carcinoma|
|Study Type :||Observational|
|Estimated Enrollment :||300 participants|
|Official Title:||Digestive Tract Tumor Research Based on ctDNA Methylation Detection Technology and Early Non-invasive Screening: Exploration and Verification of DNA Methylolation in Early Screening of Esophageal Cancer|
|Actual Study Start Date :||March 1, 2019|
|Estimated Primary Completion Date :||December 31, 2020|
|Estimated Study Completion Date :||March 31, 2021|
Early esophageal cancer group
Pathological examination diagnosed as Early esophageal cancer.The ratio of male to female is 3:1, and the age is between 50 and 70 years old.
Middle and advanced ES group
Pathological examination diagnosed as Middle and advanced esophageal cancer.
Confirmed as the normal by health checkups.
- Hydroxymethylation level [ Time Frame: up to 2 years ]To compare the differences in hydroxymethylation levels among patients in different groups, to identify the hydroxymethylation genes associated with esophageal squamous cell carcinoma, and to verify the genes related to esophageal squamous cell carcinoma by ctDNA hydroxymethylation.
Biospecimen Retention: Samples With DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03922230
|Contact: kaican firstname.lastname@example.org|
|Nanfang Hospital of Southern Medical University||Recruiting|
|Guangzhou, Guangdong, China, 510515|
|Contact: Kaican Cai, MD 8620-61641822 email@example.com|
|Study Director:||kaican cai||Nanfang Hospital of Southern Medical University|