Selective Criteria and a Modified Technique of Applying "URAGPI" Technique for More Proximal Degree of Hypospadias
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|ClinicalTrials.gov Identifier: NCT03911635|
Recruitment Status : Not yet recruiting
First Posted : April 11, 2019
Last Update Posted : April 11, 2019
Hypospadias is a condition in which the location of the urethral meatus is on the ventral aspect of the penis.
Hypospadias is the most common congenital anomaly of urogenital organs in boys, with an incidence of approximately 1 in 250 newborns. Recently, case selection has been advised to avoid possible complications and limitations . The meatal advancement and glanuloplasty (MAGPI) procedure was first described in 1981 for the repair of distal hypospadias. An excellent surgical result requires careful case selection, avoiding cases with thin or rigid ventral para-meatal skin or a meatus too proximal or too wide. The glans wrap to support the advanced ventral urethral wall requires a solid tissue approximation in two layers to prevent regression of the meatus. Meatal stenosis can be avoided by assuring an adequate dorsal Heineke- Mikulicz tissue rearrangement and making an incision from within the urethral meatus well distally into the urethral groove. . The overall success rate with the MAGPI procedure suggests that it should continue to be used in the repair of distal hypospadias . The advantage of Urethral advancement, Glanuloplasty, and Preputioplasty " URAGPI" versus MAGPI Is that A) Applicability to almost any type of distal hypospadias regardless of the severity of glanular ventriflexion.
B) Normal appearance of the penis. C) Good functional results.
|Condition or disease||Intervention/treatment||Phase|
|Hypospadias||Procedure: URAGPI technique||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||75 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Official Title:||Applying of Urethral Advancement, Glanuloplasty and Preputioplasty Technique for More Proximal Degrees of Hypospadias. Selective Criteria and a Modified Technique|
|Estimated Study Start Date :||April 1, 2019|
|Estimated Primary Completion Date :||January 1, 2021|
|Estimated Study Completion Date :||March 1, 2021|
Experimental: Hypospadias in children
Distal shaft hypospadias at age of 12 years or less
Procedure: URAGPI technique
the Urethral Advancement, Glanuloplasty and Preputioplasty
- Assessment of the patient immediately after removal of the catheter at the 7th day and after 3 weeks [ Time Frame: 3 weeks ]evaluation according to "Hypospadias Objective Penile Evaluation Score"