Physiological Phenotyping of Respiratory Outcomes in Infants Born Premature (P3)
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT03906708|
Recruitment Status : Recruiting
First Posted : April 8, 2019
Last Update Posted : January 21, 2022
|Condition or disease||Intervention/treatment|
|Premature Lungs||Other: Diffusion Capacity of the Lung for Carbon Monoxide (DLCO)|
|Study Type :||Observational|
|Estimated Enrollment :||225 participants|
|Official Title:||Physiological Phenotyping of Respiratory Outcomes in Infants Born Premature|
|Actual Study Start Date :||January 1, 2019|
|Estimated Primary Completion Date :||January 2023|
|Estimated Study Completion Date :||January 2024|
Premature infants born between 24+0 and 36+6 weeks of gestation.
Other: Diffusion Capacity of the Lung for Carbon Monoxide (DLCO)
Infant lung function testing
- Infant lung development measured by diffusion lung capacity (DLCO). [ Time Frame: By 5 months CGA. ]To characterize respiratory phenotypes through specific physiologic measures that quantify and identify predominant small airways, parenchymal and vascular dysfunction at 4 months CA and determine whether these phenotypes define risks for late respiratory morbidity during infancy.
Biospecimen Retention: Samples With DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03906708
|Contact: Jeff Bjerregaard, RRT-NPS||317 944 email@example.com|
|Contact: Lisa Bendy, BA, RPFT||317 278 firstname.lastname@example.org|
|Principal Investigator:||Robert Tepper, MD||Indiana University School of Medicine|