Restore Motor Function Through Robotic Arm Exoskeleton and Brain Computer Interface (REMAP)
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ClinicalTrials.gov Identifier: NCT03900247
Recruitment Status :
Enrolling by invitation
First Posted : April 2, 2019
Last Update Posted : April 2, 2019
University of Aarhus
University of Aalborg, Denmark
The Danish National Rehabilitation Center for Neuromuscular Diseases
The current project will aid patients with motor impairment to reduce the need for homecare. Specifically the aim is to develop and implement a robotic exoskeleton and brain computer interface to assist and eventually perform arm and hand movement in patients with the progressive neurodegenerative disease ALS. This proposal brings together state-of-the-art robotic technology, EEG-based brain computer interface (BCI) know-how, clinical expertise, patient perspective and industrial partners to develop and implement a robotic arm/hand device that will adapt, with increasing brain-computer control, based on the need of the patient. In short the BCI will measure electroencephalography (EEG) from the surface of the scalp and recognize signature EEG as the patient intents to move. As the patient loses muscle power the BCI robotic-device will gradually take over and support motor activity, even when the patient is totally paralyzed. As the device supports hand/arm function only, the investigators aim to address ADLs associated to hand function, specifically eating activities.
Condition or disease
Amyotrophic Lateral Sclerosis
Device: REMAP EEG based BCI and SEM-Glove BioServo
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Layout table for eligibility information
Ages Eligible for Study:
18 Years to 90 Years (Adult, Older Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
ALS according to the latest revision of El Escorial Criteria (Ludorph et al. 2015)
Loss of muscle force or fine motor skills in a hand
Other severe Neurological or Psychiatric disease
Drug or Alcohol dependency
Severe cognitive disturbances found to impede with study completion