Direct Acting Antivirals for HCV Infection in Kidney Transplant Recipients
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|ClinicalTrials.gov Identifier: NCT03880682|
Recruitment Status : Active, not recruiting
First Posted : March 19, 2019
Last Update Posted : July 1, 2019
|Condition or disease|
|Kidney Transplant; Complications Hepatitis C, Chronic|
|Study Type :||Observational|
|Estimated Enrollment :||40 participants|
|Official Title:||Treatment of Chronic Hepatitis C Virus Infection With Direct Acting Antivirals in Kidney Transplant Recipients|
|Actual Study Start Date :||November 1, 2018|
|Actual Primary Completion Date :||June 15, 2019|
|Estimated Study Completion Date :||October 2019|
Kidney transplant recipients with chronic HCV infection who were treated using direct acting antivirals.
- SVR12 [ Time Frame: 6 months ]Undetectable levels of HCV RNA for 12 weeks after the end of treatment with direct acting antivirals.
- Stable Graft Function [ Time Frame: 6-12 months ]Stability of serum creatinine and proteinuria levels of kidney transplant recipients during and after the treatment with direct acting antivirals.
- Stable Serum Trough Levels of Immunosuppressive Agents [ Time Frame: 6 months ]Stability of serum trough levels of calcineurin and mTOR inhibitors during the treatment with direct acting antivirals.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03880682
|Principal Investigator:||Safak Mirioglu, MD||Department of Internal Medicine, Istanbul Faculty of Medicine|
|Study Chair:||Halil Yazici, MD||Department of Internal Medicine, Istanbul Faculty of Medicine|
|Study Chair:||Sabahattin Kaymakoglu, MD||Department of Internal Medicine, Istanbul Faculty of Medicine|