Influence of Yogic Breathwork on CSF Circulation (CSF)
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|ClinicalTrials.gov Identifier: NCT03858309|
Recruitment Status : Recruiting
First Posted : February 28, 2019
Last Update Posted : July 24, 2019
|Condition or disease||Intervention/treatment||Phase|
|CSF Circulation||Behavioral: Breathing Group 1 Behavioral: Breathing Group 2||Not Applicable|
The purpose of this research protocol is to determine the influence of an 8-week breathing intervention on cerebrospinal fluid (CSF) circulation among healthy participants using a non-invasive real-time phase-contrast magnetic imaging (RT-PCMRI) technique. This aim will be examined by studying the changes in each participant's pre- and post-intervention CSF flow dynamics using the non-invasive RT-PCMRI technique during two MRI scans (one before and one after the 8-week intervention).
The study protocol consists of 20 healthy participants (two groups; 10 in each group with different breathing practices) undergoing an 8-week intervention, and pre-and post-intervention outcome measures.
The two 8-week interventions will be guided by two separate certified experienced yoga teachers. Both interventions will consist of 60-minute weekly group on-site sessions (1day/week) with a 20-minute daily home sessions (in between on-site sessions; 6 days/week) using home-aid practice materials. Participants' respiration data will be objectively tracked using a wearable respiration tracker device.
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||20 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||Single (Outcomes Assessor)|
|Primary Purpose:||Basic Science|
|Official Title:||Quantifying the Influence of Yogic Breathwork on Cerebrospinal Fluid Circulation|
|Actual Study Start Date :||July 10, 2019|
|Estimated Primary Completion Date :||February 1, 2020|
|Estimated Study Completion Date :||February 1, 2021|
Experimental: Breathing Group 1
Arm 1 will receive an 8-week intervention that consists of a set of breathing practices through 60-minute weekly group on-site sessions (1day/week) with a 20-minute daily home sessions (in between on-site sessions; 6 days/week).
Behavioral: Breathing Group 1
The 8-week breathwork intervention incorporates a set of breathing practices under the guidance of a certified yoga teacher.
Active Comparator: Breathing Group 2
Arm 2 will receive an 8-week intervention that consists of slow breathing practices through 60-minute weekly group on-site sessions (1day/week) with a 20-minute daily home sessions (in between on-site sessions; 6 days/week).
Behavioral: Breathing Group 2
The 8-week breathwork intervention incorporates a set of slow breathing practices under the guidance of a certified yoga teacher.
- CSF Flow Velocities [ Time Frame: Once before and after the 8-week intervention ]The changes in pre- and post- intervention CSF flow velocities will be measured using a non-invasive MRI approach.
- Systolic and Diastolic Blood Pressure [ Time Frame: Once before and once after the 8-week intervention ]The changes in pre- and post-intervention blood pressure will be measured.
- Body Mass Index (BMI) [ Time Frame: Once before and once after the 8-week intervention ]The changes in pre- and post-intervention BMI will be measured. The BMI is derived from each participant's height and weight information.
- Respiration [ Time Frame: Respiration data will be collected when participants are performing the breathing practices during the weekly on-site sessions (60-minute/week) and daily home practice (20-minute/day) over the course of 8-week intervention. ]Respiration phases will be measured using a wearable respiration tracker to objectively track respiration of participants throughout the interventions.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03858309
|United States, Oregon|
|Oregon Health & Science University||Recruiting|
|Portland, Oregon, United States, 97239|
|Principal Investigator:||Yildiz||Oregon Health and Science University|